{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:03:47Z","timestamp":1777907027662,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2013,9,16]],"date-time":"2013-09-16T00:00:00Z","timestamp":1379289600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:p>We describe the epidemiological, clinical features and risk factors for the morbidity and mortality of imported Plasmodium falciparum malaria cases during the last 10 years in Istanbul, Turkey. The epidemiological, clinical and laboratory data of cases in six tertiary care hospitals in Istanbul between 2002 and 2012 were analysed. Seventy patients (65 males, five females; median age 37; range: 14\u201384) were included. Sixty-five (93%) patients had travelled to African countries and the remaining five to other malarious countries. Seventeen (24%) had a history of previous malarial episodes; eight (13%) developed recrudescence during the first month; 22 (31%), 17 (24%), 20 (29%) and three (4%) cases had cerebral malaria, cholestatic icterus, malarial hepatitis and respiratory distress syndrome on admission, respectively. Six of 12 patients with severe falciparum malaria died. Clinically, the presence of alteration in mental status, icterus, hypoglycaemia, disseminated intravascular coagulation and malarial hepatitis were statistically significant for the development of severe malaria and mortality. Recrudescence should not be forgotten, especially in uncomplicated cases.<\/jats:p>","DOI":"10.1177\/0049475513499560","type":"journal-article","created":{"date-parts":[[2013,9,16]],"date-time":"2013-09-16T23:04:45Z","timestamp":1379372685000},"page":"129-133","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Imported\n                    <i>Plasmodium falciparum<\/i>\n                    malaria in Istanbul, Turkey: risk factors for severe course and mortality"],"prefix":"10.1177","volume":"43","author":[{"given":"Ferhat","family":"Arslan","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Infectious Diseases and Clinical Microbiology, Istanbul Medipol University, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ali","family":"Mert","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Infectious Diseases and Clinical Microbiology, Istanbul Medipol University, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayse","family":"Batirel","sequence":"additional","affiliation":[{"name":"Doctor, Department of Infectious Diseases and Clinical Microbiology, Kartal Dr Lutfi Kirdar Education and Research Hospital, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asuman","family":"Inan","sequence":"additional","affiliation":[{"name":"Doctor, Department of Infectious Diseases and Clinical Microbiology, Haydarpasa Education and Research Hospital, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilker Inanc","family":"Balkan","sequence":"additional","affiliation":[{"name":"Doctor, Department of Infectious Diseases and Clinical Microbiology, Cerrahpasa Medical Faculty, Istanbul University, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozcan","family":"Nazlican","sequence":"additional","affiliation":[{"name":"Doctor, Department of Infectious Diseases and Clinical Microbiology, Haseki Education and Research Hospital, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cengiz","family":"Uzun","sequence":"additional","affiliation":[{"name":"Doctor, Department of Infectious Diseases and Clinical Microbiology, Universal Taksim German Hospital, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haluk","family":"Vahaboglu","sequence":"additional","affiliation":[{"name":"Professor and Doctor, Department of Infectious Diseases and Clinical Microbiology, Goztepe Education and Research Hospital, Istanbul Medeniyet University, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,9,16]]},"reference":[{"key":"bibr1-0049475513499560","doi-asserted-by":"publisher","DOI":"10.3184\/003685009X440290"},{"key":"bibr2-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1596\/978-0-8213-8376-6"},{"key":"bibr3-0049475513499560","first-page":"1","volume":"61","author":"Mali S","year":"2012","journal-title":"MMWR Surveill Summ"},{"key":"bibr4-0049475513499560","doi-asserted-by":"crossref","unstructured":"Gautret P, Cramer JP, Field V, et\u00a0al. for the EuroTravNet network. Infectious diseases among travellers and migrants in Europe, EuroTravNet 2010.\n                      Euro Surveill\n                      2012; 17. Retrieved from: http:\/\/www.eurosurveillance.org\/ViewArticle.aspx?Article id=20205.","DOI":"10.2807\/ese.17.26.20205-en"},{"key":"bibr5-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1186\/cc2183"},{"key":"bibr6-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(00)90300-6"},{"key":"bibr7-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2005.03884.x"},{"key":"bibr8-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-397900-1.00002-5"},{"key":"bibr9-0049475513499560","unstructured":"\u015e\u2009\u2009atana NS, Dikleli ER, \u0130lerler AR, Gencer S, Dokucu A\u0130. Epidemiological evaluation of malaria cases diagnosed in Istanbul, Turkey between 2002 and 2011. SS-008. Available at: www.ekmud.org\/dosya\/ekm12\/ekmud2012kitap.pdf."},{"key":"bibr10-0049475513499560","volume-title":"Guidelines for the Treatment of Malaria","author":"World Health Organization","year":"2010","edition":"2"},{"key":"bibr11-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e2116"},{"key":"bibr12-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1086\/374224"},{"key":"bibr13-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1177\/0885066609356052"},{"key":"bibr14-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199505253322102"},{"key":"bibr15-0049475513499560","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0013236"},{"key":"bibr16-0049475513499560","first-page":"749479","volume":"2012","author":"Ndounga M","year":"2012","journal-title":"Malar Res Treat"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475513499560","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475513499560","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475513499560","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:28:38Z","timestamp":1777642118000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475513499560"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,9,16]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["10.1177\/0049475513499560"],"URL":"https:\/\/doi.org\/10.1177\/0049475513499560","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,9,16]]}}}