{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:04:57Z","timestamp":1777907097234,"version":"3.51.4"},"reference-count":70,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2015,9,7]],"date-time":"2015-09-07T00:00:00Z","timestamp":1441584000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Human immunodeficiency virus (HIV) infection is likely to have untoward effects on pregnancy and its outcome. This study assessed the impact of maternal HIV infection on pregnancy outcomes in a tertiary centre in Calabar, Nigeria.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This retrospective study analysed delivery records of 258 HIV-positive and 257 HIV-negative women for pregnancy and delivery complications. Maternal and fetal outcomes of HIV-positive pregnancies were compared with those of HIV-negative controls.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Adverse pregnancy outcomes significantly associated with HIV status were: anaemia: 33 (8.1%) vs. 8 (3.1%) in controls; puerperal sepsis: 18 (7%) vs. 2 (0.8%); and low birth weight: 56 (21.7%) vs. 37 (14.4%). Caesarean delivery was higher among HIV-positive women than controls: 96 (37.2%) vs. 58 (22.6%). Preterm births were higher in those HIV cohorts who did not receive antiretroviral therapy (ART): 13 (16.9%) vs. 7 (3.9%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>HIV-positive status increased adverse birth outcome of pregnancy. ART appeared to reduce the risk of preterm births in HIV-positive cohorts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0049475515605003","type":"journal-article","created":{"date-parts":[[2015,9,8]],"date-time":"2015-09-08T19:58:07Z","timestamp":1441742287000},"page":"78-86","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["HIV infection in pregnancy: maternal and perinatal outcomes in a tertiary care hospital in Calabar, Nigeria"],"prefix":"10.1177","volume":"46","author":[{"given":"Ekott Mabel","family":"Ikpim","sequence":"first","affiliation":[{"name":"Reader, Department of Obstetrics & Gynaecology, University of Calabar, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Udo Atim","family":"Edet","sequence":"additional","affiliation":[{"name":"Reader, Department of Obstetrics & Gynaecology, University of Calabar, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akpan Ubong","family":"Bassey","sequence":"additional","affiliation":[{"name":"Lecturer , Department of Obstetrics & Gynaecology, University of Calabar, Calabar, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Otu Akaninyene","family":"Asuquo","sequence":"additional","affiliation":[{"name":"Lecturer, Department of Internal Medicine, University of Calabar, Calabar, Cross River State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ekanem Etim","family":"Inyang","sequence":"additional","affiliation":[{"name":"Lecturer, Department of Internal Medicine, University of Calabar, Calabar, Cross River State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,9,7]]},"reference":[{"key":"bibr1-0049475515605003","volume-title":"HIV\/AIDS factsheet","author":"World Health Organization","year":"2015"},{"key":"bibr2-0049475515605003","volume-title":"Sub-Saharan Africa. 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