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The pathogenesis is due to an exaggerated immune response to the filarial antigens which includes type I, type III and type IV reactions with eosinophils playing a pivotal role. Leucocytosis with an absolute increase in eosinophils in the peripheral blood is the hallmark of TPE. Other criteria for the diagnosis of TPE include high titres of antifilarial antibodies, raised serum total IgE\u2009&gt;\u20091000\u2009ku\/L and a favourable response to the antifilarial agent, diethyl-carbamazine. Although TPE runs a benign course, if left untreated, it could result in a fair degree of respiratory morbidity.<\/jats:p>","DOI":"10.1177\/0049475515606011","type":"journal-article","created":{"date-parts":[[2015,9,16]],"date-time":"2015-09-16T22:34:32Z","timestamp":1442442872000},"page":"105-108","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["A rare presentation of hydropneumothorax in tropical pulmonary eosinophilia: cavitation and pneumonic consolidation in a child"],"prefix":"10.1177","volume":"46","author":[{"given":"Saurabh","family":"Kumar","sequence":"first","affiliation":[{"name":"Department Of Paediatrics, St Stephens Hospital, Tis Hazari, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajbeer Singh","family":"Beri","sequence":"additional","affiliation":[{"name":"Department Of Paediatrics, St Stephens Hospital, Tis Hazari, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2015,9,16]]},"reference":[{"key":"bibr1-0049475515606011","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)70615-5"},{"key":"bibr2-0049475515606011","first-page":"205","volume":"43","author":"Prasad R","year":"1996","journal-title":"Ind J Tub"},{"key":"bibr3-0049475515606011","first-page":"231","volume":"5","author":"Menon NK","year":"1963","journal-title":"Indian J Chest Dis"},{"key":"bibr4-0049475515606011","first-page":"257","volume":"17","author":"Viswanathan R","year":"1948","journal-title":"Q J Med"},{"key":"bibr5-0049475515606011","first-page":"141","volume":"20","author":"Nath J","year":"1978","journal-title":"Indian J Chest Dis Allied Sci"},{"key":"bibr6-0049475515606011","first-page":"135","volume":"17","author":"Mital OP","year":"1975","journal-title":"Indian J Chest Dis"},{"key":"bibr7-0049475515606011","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-36-432-889"},{"key":"bibr8-0049475515606011","first-page":"35","volume-title":"Pulmonary Eosinophilia: Progress in Respiration Research","author":"Udwadia FE","year":"1975"},{"key":"bibr9-0049475515606011","first-page":"251","volume":"83","author":"Khoo FY","year":"1960","journal-title":"Am J Roentgenol Radium Ther Nucl Med"},{"key":"bibr10-0049475515606011","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.5295.1810-a"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475515606011","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475515606011","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475515606011","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:29:38Z","timestamp":1777642178000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475515606011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,9,16]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["10.1177\/0049475515606011"],"URL":"https:\/\/doi.org\/10.1177\/0049475515606011","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,9,16]]}}}