{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T17:07:48Z","timestamp":1793812068470,"version":"4.6.1"},"reference-count":17,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2016,7,10]],"date-time":"2016-07-10T00:00:00Z","timestamp":1468108800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2016,10]]},"abstract":"<jats:p>Cerebral malaria (CM) is a diffuse encephalopathy associated with coma and seizures commonly caused by Plasmodium falciparum ( P. falciparum) in children with severe malaria. We present a case of a 19-year-old man with CM due to Plasmodium vivax ( P. vivax) infection. Cerebrospinal fluid (CSF) was negative for Japanese B encephalitis, enterovirus, herpes simplex 1 and 2, varicella and mumps viruses as determined by real-time polymerase chain reaction (PCR). P. falciparum and P. vivax species were analysed by microscopy, immunochromatography and PCR assays and confirmed mono-infection of P. vivax in the patient\u2019s blood, and P. falciparum infection was established to be negative. The patient was discharged after intensive supportive care and antimalarial treatment (intravenous artesunate and oral doxycycline). We conclude that P. vivax infection is associated with CM, a life-threatening complication rarely seen in coastal districts of Karnataka. In endemic areas, the possibility of CM should be considered even with P. vivax infection.<\/jats:p>","DOI":"10.1177\/0049475515624857","type":"journal-article","created":{"date-parts":[[2016,1,9]],"date-time":"2016-01-09T20:17:58Z","timestamp":1452370678000},"page":"241-245","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Cerebral malaria in a man with\n                    <i>Plasmodium vivax<\/i>\n                    mono-infection: a case report"],"prefix":"10.1177","volume":"46","author":[{"given":"Himanshu","family":"Gupta","sequence":"first","affiliation":[{"name":"Research Scholar, Department of Biotechnology, School of Life Sciences, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pushwinder","family":"Dhunputh","sequence":"additional","affiliation":[{"name":"Senior Resident, Department of Medicine, Dr. TMA Pai Hospital, Udupi, Melaka Manipal Medical College, Manipal University, Manipal, Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankita N","family":"Bhatt","sequence":"additional","affiliation":[{"name":"Junior Resident, Department of Medicine, Dr. TMA Pai Hospital, Udupi, Melaka Manipal Medical College, Manipal University, Manipal, Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kapaettu","family":"Satyamoorthy","sequence":"additional","affiliation":[{"name":"Professor and Director, Department of Biotechnology, School of Life Sciences, Manipal University, Manipal, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashikiran","family":"Umakanth","sequence":"additional","affiliation":[{"name":"Professor and Head, Department of Medicine, Department of Medicine, Dr. TMA Pai Hospital, Udupi, Melaka Manipal Medical College, Manipal University, Manipal, Karnataka India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2016,7,10]]},"reference":[{"key":"bibr1-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-86702005000500011"},{"key":"bibr2-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1111\/j.1708-8305.2006.0064_1.x"},{"key":"bibr3-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1179\/1465328111Y.0000000040"},{"key":"bibr4-0049475515624857","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2009.80.194"},{"key":"bibr5-0049475515624857","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.6813"},{"key":"bibr6-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-304"},{"key":"bibr7-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-370"},{"key":"bibr8-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090419"},{"key":"bibr9-0049475515624857","first-page":"1205","volume-title":"Manson\u2019s Tropical Diseases","author":"White NJ","year":"2002","edition":"21"},{"key":"bibr10-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2004.03.006"},{"key":"bibr11-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2013.08.005"},{"key":"bibr12-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1086\/654815"},{"key":"bibr13-0049475515624857","first-page":"33","volume":"105","author":"Chotivanich K","year":"2003","journal-title":"Exp Parasitol"},{"key":"bibr14-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1097\/00003246-200103000-00037"},{"key":"bibr15-0049475515624857","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-11-35"},{"issue":"1","key":"bibr16-0049475515624857","first-page":"7","volume":"19","author":"WHO","year":"2014","journal-title":"Trop Med Int Health"},{"key":"bibr17-0049475515624857","unstructured":"Wahlgren M, Perlmann P, eds.\n                      Malaria: Molecular and Clinical Aspects\n                      . 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