{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:06:20Z","timestamp":1777907180374,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2017,2,26]],"date-time":"2017-02-26T00:00:00Z","timestamp":1488067200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:p>Dengue is endemic in more than 100 countries, giving rise to an increased number of deaths in the last five years in the South-East Asian region. We report our findings from a retrospective study of adults admitted with confirmed dengue at our institution. We studied the clinical and laboratory parameters associated with mortality in these patients. Of the 172 hospitalised patients studied, 156 (90.69 %) recovered while 16 (9.3%) died. Univariate analysis showed altered sensorium on presentation, lower haemoglobin and haematocrit levels, higher serum creatinine, higher serum transaminase and lower serum albumin levels to be significantly associated with mortality in dengue. Further, using stepwise multivariate logistic regression, altered sensorium ( P\u2009=\u20090.006) and hypoalbuminemia ( P\u2009=\u20090.013) were identified as independent predictors of mortality in dengue. Identification of these parameters early in the course of disease should prompt intensification of treatment in dengue cases.<\/jats:p>","DOI":"10.1177\/0049475517693993","type":"journal-article","created":{"date-parts":[[2017,2,27]],"date-time":"2017-02-27T01:44:45Z","timestamp":1488159885000},"page":"141-145","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Clinical and laboratory factors associated with mortality in dengue"],"prefix":"10.1177","volume":"47","author":[{"given":"Atul","family":"Saroch","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Medicine, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vivek","family":"Arya","sequence":"additional","affiliation":[{"name":"Professor, Department of Medicine, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nitin","family":"Sinha","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Medicine, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RS","family":"Taneja","sequence":"additional","affiliation":[{"name":"Professor, Department of Medicine, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pooja","family":"Sahai","sequence":"additional","affiliation":[{"name":"Senior Resident, Department of Microbiology, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"RK","family":"Mahajan","sequence":"additional","affiliation":[{"name":"Professor, Department of Microbiology, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,2,26]]},"reference":[{"key":"bibr1-0049475517693993","unstructured":"World Health Organization.\n                      Comprehensive guidelines for prevention and control of dengue and dengue hemorrhagic fever\n                      . Geneva: WHO, 2011."},{"key":"bibr2-0049475517693993","unstructured":"World Health Organization.\n                      Dengue guidelines for diagnosis, treatment, prevention and control\u2009-\u2009New edition\n                      . Geneva: WHO, 2009."},{"key":"bibr3-0049475517693993","doi-asserted-by":"publisher","DOI":"10.1177\/004947559902900110"},{"key":"bibr4-0049475517693993","doi-asserted-by":"publisher","DOI":"10.5455\/ijmsph.2013.2.252-255"},{"key":"bibr5-0049475517693993","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2007.09.040"},{"key":"bibr6-0049475517693993","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181bd8258"},{"key":"bibr7-0049475517693993","doi-asserted-by":"publisher","DOI":"10.3109\/13550289809114548"},{"key":"bibr8-0049475517693993","first-page":"333","volume":"41","author":"Almas A","year":"2001","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"bibr9-0049475517693993","doi-asserted-by":"publisher","DOI":"10.3855\/jidc.2010"},{"key":"bibr10-0049475517693993","doi-asserted-by":"publisher","DOI":"10.47102\/annals-acadmedsg.V37N1p82"},{"key":"bibr11-0049475517693993","first-page":"127","volume":"18","author":"Itha S","year":"2005","journal-title":"Natl Med J India"},{"key":"bibr12-0049475517693993","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0129046"},{"key":"bibr13-0049475517693993","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2011.05.008"},{"key":"bibr14-0049475517693993","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v3.i2.125"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475517693993","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475517693993","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475517693993","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:30:23Z","timestamp":1777642223000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475517693993"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,26]]},"references-count":14,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["10.1177\/0049475517693993"],"URL":"https:\/\/doi.org\/10.1177\/0049475517693993","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,26]]}}}