{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:06:09Z","timestamp":1777907169002,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,6,6]],"date-time":"2017-06-06T00:00:00Z","timestamp":1496707200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2017,10]]},"abstract":"Bacterial meningitis is an important cause of death and disability in sub-Saharan Africa and, with pre-treatment in peripheral health centres, the poorest populations could avoid early death, especially if they live far from hospital.<\/jats:p>\n During the 2001 meningitis epidemic in south Chad, Moyen Chari sanitary district peripheral health centres were equipped with oily chloramphenicol (CAP) to administer before hospital referral in suspected cases of meningitis. Eighty-six patients treated with CAP in whom the diagnosis was definitively confirmed subsequently in hospital were compared with patients receiving CAP at hospital admission during the same period.<\/jats:p>\n A statistically significant reduction in lethality rate, need of second line treatment or adjunctive antibiotics, and mean hospital stay were confirmed in pre-treated patients.<\/jats:p>","DOI":"10.1177\/0049475517710397","type":"journal-article","created":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T01:30:28Z","timestamp":1496799028000},"page":"328-331","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Pre-hospital oily chloramphenicol treatment in meningitis outbreaks in low resources environments"],"prefix":"10.1177","volume":"47","author":[{"given":"Enrico Rino","family":"Bregani","sequence":"first","affiliation":[{"name":"MD, Emergency Medicine Division, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"},{"name":"MD, H\u00f4pital de Goundi, Association Tchadienne Communaut\u00e9 pour le Progr\u00e8s, Chad"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matilde","family":"Conti","sequence":"additional","affiliation":[{"name":"MD, Emergency Medicine Division, Fondazione IRCCS Ca\u2019 Granda Ospedale Maggiore Policlinico, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caterina","family":"Valcarenghi","sequence":"additional","affiliation":[{"name":"MD, Scuola di Specialit\u00e0 di Anestesia, Rianimazione, Terapia Intensiva e del Dolore, Universit\u00e0 degli Studi di Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,6,6]]},"reference":[{"key":"bibr1-0049475517710397","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.04.036"},{"key":"bibr2-0049475517710397","unstructured":"World Health Organization.\n Meningococcal meningitis. 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