{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:05:35Z","timestamp":1777907135487,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2017,6,7]],"date-time":"2017-06-07T00:00:00Z","timestamp":1496793600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p>Most of the studies on the appropriate dose of anti-snake venom (ASV) are from tertiary hospitals and the guidelines are unclear. Our observational study compared the outcomes of two prevalent treatment regimes for haematotoxic snake bite in a secondary care hospital in South India. The time to normalisation of whole blood clotting time, mortality and complications were not different between the groups. The average dose of ASV required in the low and high dose groups were 106\u2009mL and 246\u2009mL, respectively. Consequently, patients who received low dose ASV incurred approximately 50% less expense. Urticarial rashes were also significantly fewer in the low dose group.<\/jats:p>","DOI":"10.1177\/0049475517712804","type":"journal-article","created":{"date-parts":[[2017,6,8]],"date-time":"2017-06-08T01:19:43Z","timestamp":1496884783000},"page":"300-304","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Low dose versus high dose anti-snake venom therapy in the treatment of haematotoxic snake bite in South India"],"prefix":"10.1177","volume":"47","author":[{"given":"Imanto M","family":"Joseph","sequence":"first","affiliation":[{"name":"DNB General Medicine Senior Resident, Dr Somervell Memorial CSI Medical College, Karakonam, Thiruvananthapuram, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cijoy K","family":"Kuriakose","sequence":"additional","affiliation":[{"name":"DNB General Medicine Assistant Professor, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand Vimal","family":"Dev","sequence":"additional","affiliation":[{"name":"DNB General Medicine Postgraduate Registrar, Christian Medical College and Hospital, Vellore, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George A","family":"Philip","sequence":"additional","affiliation":[{"name":"DNB General Medicine Senior Consultant, Christian Fellowship Hospital, Oddanchatram, Tamil Nadu, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2017,6,7]]},"reference":[{"key":"bibr1-0049475517712804","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61754-2"},{"key":"bibr2-0049475517712804","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0707885104"},{"key":"bibr3-0049475517712804","unstructured":"World Health Organization. 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