{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T20:46:58Z","timestamp":1790628418188,"version":"4.1.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T00:00:00Z","timestamp":1517529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:p>Snakebite associated with a venom-induced consumption coagulopathy (VICC) is a major public health problem. Our study aims to evaluate if fresh frozen plasma (FFP), administered after anti-snake venom (ASV), restores coagulability rapidly. At admission, all snakebite victims with a whole blood clotting time (WBCT)\u2009&gt;20\u2009min received ten vials of ASV according to World Health Organization criteria. After 6\u2009h, at the discretion of the physician, patients with WBCT\u2009&gt;20\u2009min were divided into two groups. The test group received both ASV and FFP and the control group received ASV only. The mean number of ASVs used in tests and controls were 17 and 31, respectively. The clotting time normalised at 24\u2009h and 42\u2009h in the test group and control group, respectively. FFP appears to aid restoration of clotting factors more rapidly and thus haemorrhage and the number of anti-snake venom vials used are both reduced.<\/jats:p>","DOI":"10.1177\/0049475518756083","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T07:51:34Z","timestamp":1517557894000},"page":"89-93","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":25,"title":["The role of fresh frozen plasma in reducing the volume of anti-snake venom in snakebite envenomation"],"prefix":"10.1177","volume":"48","author":[{"given":"Subraya Krishna","family":"Holla","sequence":"first","affiliation":[{"name":"Department of General Medicine, Kasturba Medical College, Manipal University, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harish A","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kasturba Medical College, Manipal University, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damodara","family":"Shenoy","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kasturba Medical College, Manipal University, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archith","family":"Boloor","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kasturba Medical College, Manipal University, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manaswitha","family":"Boyanagari","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kasturba Medical College, Manipal University, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,2,2]]},"reference":[{"key":"bibr1-0049475518756083","doi-asserted-by":"publisher","DOI":"10.4172\/2161-0495.1000182"},{"issue":"1","key":"bibr2-0049475518756083","first-page":"1","volume":"30","author":"Warrell DA","year":"1999","journal-title":"Southeast Asian J Trop Med Public Health"},{"key":"bibr3-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61754-2"},{"key":"bibr4-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2009.11.020"},{"key":"bibr5-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-009-1556-7"},{"key":"bibr6-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcp081"},{"key":"bibr7-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1177\/0310057X0503300106"},{"key":"bibr8-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1136\/emj.2004.022251"},{"key":"bibr9-0049475518756083","doi-asserted-by":"publisher","DOI":"10.1016\/0041-0101(86)90037-1"},{"key":"bibr10-0049475518756083","unstructured":"Standard Treatment Guidelines \u2013 Governnment of India. 2017. 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