{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:05:55Z","timestamp":1777907155171,"version":"3.51.4"},"reference-count":13,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2018,5,14]],"date-time":"2018-05-14T00:00:00Z","timestamp":1526256000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:p>In order to study the bacteriological profile, antibiotic sensitivity and outcome following empirical therapy with early generation antibiotics in patients with deep head and neck infection, a retrospective review of 42 patients admitted for drainage and intravenous antibiotic therapy was performed. Ludwig\u2019s angina was the commonest infection, with the most common organisms isolated being Group F \u00df-haemolytic (15%) and non-haemolytic (12.5%) streptococcus. All streptococci and anaerobic gram-positive cocci were susceptible to penicillin. S. aureus isolates were oxacillin-sensitive and enterococcus isolates were ampicillin-sensitive. All 42 patients received empirical therapy with either intravenous penicillin or its derivatives. In only three patients was a change of antibiotic required based on culture and sensitivity results. Early generation antibiotics appear ideal as empirical therapy for deep head and neck infection.<\/jats:p>","DOI":"10.1177\/0049475518774472","type":"journal-article","created":{"date-parts":[[2018,5,14]],"date-time":"2018-05-14T22:54:52Z","timestamp":1526338492000},"page":"179-182","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Deep head and neck infections: outcome following empirical therapy with early generation antibiotics"],"prefix":"10.1177","volume":"48","author":[{"given":"Lalee","family":"Varghese","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Otorhinolaryngology, Christian Medical College, Vellore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suma Susan","family":"Mathews","sequence":"additional","affiliation":[{"name":"Professor, Department of Otorhinolaryngology, Christian Medical College, Vellore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"John","family":"Antony Jude Prakash","sequence":"additional","affiliation":[{"name":"Professor, Department of Microbiology, Christian Medical College, Vellore"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V","family":"Rupa","sequence":"additional","affiliation":[{"name":"Professor, Department of Otorhinolaryngology, Christian Medical College, Vellore"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,5,14]]},"reference":[{"key":"bibr1-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2011.08.004"},{"key":"bibr2-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1016\/j.rcl.2010.07.013"},{"key":"bibr3-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2011.01.003"},{"key":"bibr4-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20014"},{"key":"bibr5-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1080\/00016480802008181"},{"key":"bibr6-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.05.023"},{"key":"bibr7-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2003.12.043"},{"key":"bibr8-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2009.03.033"},{"key":"bibr9-0049475518774472","first-page":"190","volume":"31","author":"Songu M","year":"2011","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"bibr10-0049475518774472","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S3554"},{"key":"bibr11-0049475518774472","first-page":"351","volume":"52","author":"Lee YQ","year":"2011","journal-title":"Singapore Med J"},{"key":"bibr12-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1186\/1916-0216-42-18"},{"key":"bibr13-0049475518774472","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciw118"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475518774472","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475518774472","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475518774472","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:31:00Z","timestamp":1777642260000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475518774472"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5,14]]},"references-count":13,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,7]]}},"alternative-id":["10.1177\/0049475518774472"],"URL":"https:\/\/doi.org\/10.1177\/0049475518774472","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,5,14]]}}}