{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:06:33Z","timestamp":1777907193523,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2018,8,19]],"date-time":"2018-08-19T00:00:00Z","timestamp":1534636800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:p>Leptospirosis is a serious public health concern worldwide. It is highly endemic in the Andaman Islands and its prevalence is increasing in other Indian states.<\/jats:p>\n                  <jats:p>Clinical features are non-specific and diagnosis relies on laboratory confirmation. The gold standard is microscopic agglutination testing, but this is not widely available. Real-time polymerase chain reaction testing of LipL32 antigen provides the earliest detection of pathogenic Leptospira in the body. We found it to be 100% specific, but it should be used in the first 10 days of illness for reliable results.<\/jats:p>","DOI":"10.1177\/0049475518788470","type":"journal-article","created":{"date-parts":[[2018,8,20]],"date-time":"2018-08-20T02:20:31Z","timestamp":1534731631000},"page":"306-309","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Leptospirosis: a diagnostic conundrum"],"prefix":"10.1177","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4509-3741","authenticated-orcid":false,"given":"Keerthivasan","family":"Gurumurthy","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Microbiology, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harish Belgode","family":"Narasimha","sequence":"additional","affiliation":[{"name":"Senior Professor, Department of Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mukta","family":"Wyawahare","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of General Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Niranjan","family":"Biswal","sequence":"additional","affiliation":[{"name":"Professor, Department of Paediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,8,19]]},"reference":[{"key":"bibr1-0049475518788470","first-page":"247","volume":"51","author":"Kamath SA","year":"2003","journal-title":"J Assoc Physicians India"},{"key":"bibr2-0049475518788470","doi-asserted-by":"publisher","DOI":"10.1097\/00001432-200110000-00005"},{"key":"bibr3-0049475518788470","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-2-13"},{"key":"bibr4-0049475518788470","unstructured":"Vijayachari P, Sharma, S and Natarajaseenivasan, K. 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