{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:07:05Z","timestamp":1777907225201,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T00:00:00Z","timestamp":1550620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2019,7]]},"abstract":"<jats:p>Cirrhotic patients with ascites are at high risk of developing spontaneous bacterial peritonitis (SBP). After exclusion of patients with acute kidney injury (AKI) or other infections, urinary neutrophil gelatinase-associated lipocalin (NGAL) levels were compared between two matched groups of Egyptian cirrhotic patients with ascites, mostly secondary to hepatitis C infection (98%). Group 1 had SBP (n\u2009=\u200941) and group 2 did not (n\u2009=\u200945). By univariate analysis, urinary-NGAL, high total bilirubin, serum creatinine, international normalised ratio and the Model of End-Stage Liver Disease (MELD) score and low platelet count were all significantly correlated with the presence of SBP, but only urinary-NGAL could independently predict development of SBP ( P\u2009=\u20090.001). Urinary-NGAL at a cut-off value of 1225\u2009pg\/mL, showed a sensitivity of 95% and a specificity of 76%, and is therefore a most useful tool.<\/jats:p>","DOI":"10.1177\/0049475519830265","type":"journal-article","created":{"date-parts":[[2019,2,20]],"date-time":"2019-02-20T20:20:46Z","timestamp":1550694046000},"page":"189-192","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Urinary neutrophil gelatinase-associated lipocalin for diagnosis of spontaneous bacterial peritonitis"],"prefix":"10.1177","volume":"49","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1542-0265","authenticated-orcid":false,"given":"Tamer R","family":"Fouad","sequence":"first","affiliation":[{"name":"Hepatology and Gastroenterology Department, National Liver Institute, Menofia University, Menofia Governate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eman","family":"Abdelsameea","sequence":"additional","affiliation":[{"name":"Hepatology and Gastroenterology Department, National Liver Institute, Menofia University, Menofia Governate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maha","family":"Elsabaawy","sequence":"additional","affiliation":[{"name":"Hepatology and Gastroenterology Department, National Liver Institute, Menofia University, Menofia Governate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Ashraf Eljaky","sequence":"additional","affiliation":[{"name":"Hepatology and Gastroenterology Department, National Liver Institute, Menofia University, Menofia Governate, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soha","family":"Zaki El-shenawy","sequence":"additional","affiliation":[{"name":"Clinical Biochemistry Department, National Liver Institute, Menofia University, 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