{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:08:22Z","timestamp":1777907302882,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:p>Chronic osteomyelitis is a relapsing, persistent, low-grade inflammation of bone caused by various infectious agents. The present study, conducted over a two-year period, on specimens received from cases of chronic osteomyelitis was, to determine the frequency of isolation of aerobic and anaerobic bacteria and to analyse their antimicrobial susceptibility pattern. Specimens were processed for Gram stain, aerobic and anaerobic culture, and were identified according to standard techniques. Significant growth was observed in 102\/204 specimens, in which aerobic growth was observed in 62 (60.8%) and anaerobic in 40 (39.2%). Resistance to metronidazole and clindamycin was observed in 6.7% and 30% of the anaerobic isolates, respectively. None of these were resistant to meropenem. A significant proportion of anaerobic isolates were found to be resistant to commonly used empirical drugs, such as clindamycin, thus necessitating a need for routine anaerobic susceptibility testing.<\/jats:p>","DOI":"10.1177\/0049475520921283","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T22:32:21Z","timestamp":1588113141000},"page":"198-202","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Microbiological profile of chronic osteomyelitis with special reference to anaerobic osteomyelitis in a tertiary care hospital of coastal Karnataka"],"prefix":"10.1177","volume":"50","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6781-5579","authenticated-orcid":false,"given":"Padmaja A","family":"Shenoy","sequence":"first","affiliation":[{"name":"Associate Professor, Department of Microbiology, Kasturba Manipal Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shashidhar","family":"Vishwanath","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Microbiology, Kasturba Manipal Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9545-4838","authenticated-orcid":false,"given":"Shyamasunder N","family":"Bhat","sequence":"additional","affiliation":[{"name":"Professor and Head, Department of Orthopaedics, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chiranjay","family":"Mukhopadhyay","sequence":"additional","affiliation":[{"name":"Professor, Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran","family":"Chawla","sequence":"additional","affiliation":[{"name":"Professor and Head, Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,4,28]]},"reference":[{"key":"bibr1-0049475520921283","first-page":"217","volume":"31","author":"Garc\u00eda Del Pozo E","year":"2018","journal-title":"Rev Esp Quimioter"},{"key":"bibr2-0049475520921283","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.1.95"},{"key":"bibr3-0049475520921283","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir842"},{"key":"bibr4-0049475520921283","first-page":"337","volume":"9","author":"Wadekar DM","year":"2014","journal-title":"Int J Recent Trends Sci Technol"},{"key":"bibr5-0049475520921283","doi-asserted-by":"publisher","DOI":"10.2174\/1874325001812010153"},{"key":"bibr6-0049475520921283","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0b013e318217ca0e"},{"key":"bibr7-0049475520921283","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-007-1207-1"},{"key":"bibr8-0049475520921283","doi-asserted-by":"crossref","first-page":"494","DOI":"10.26719\/1996.2.3.494","volume":"2","author":"Mousa HA","year":"1996","journal-title":"East Mediterr Health J"},{"key":"bibr9-0049475520921283","first-page":"181","volume":"8","author":"Ananth-Shenoy P","year":"2016","journal-title":"Iran J Microbiol"},{"key":"bibr10-0049475520921283","doi-asserted-by":"publisher","DOI":"10.4103\/JLP.JLP_14_17"},{"key":"bibr11-0049475520921283","unstructured":"Collee JG, Miles RS and Watt B. 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