{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T14:36:31Z","timestamp":1792506991845,"version":"4.5.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,12,6]],"date-time":"2020-12-06T00:00:00Z","timestamp":1607212800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Bloodstream infection remains one of the most important causes of morbidity and mortality globally, specifically among intensive care unit patients. This prospective observational study included 887 blood culture samples collected cases admitted to intensive care unit suspected of having sepsis. Samples were cultured and evaluated for antimicrobial susceptibility patterns: 202 (22.78%) blood cultures were positive and yielded microbial growth with 132 (14.88%) having mono-microbial growth. Gram-negative bacteria accounted for 45.2% cases, with Escherichia coli being the most common; Gram positives accounted for 43.9% with Staphylococci haemolyticus being most common and 10.9% were fungal isolates. Gram-negative isolates were sensitive to colistin and tigecycline and 77.3% of isolates were extended spectrum beta-lactamase (ESBL) producers. Gram-positive isolates were sensitive to tigecycline, linezolid, vancomycin and teicoplanin with 97.5% being methicillin-resistant Staphylococci (MRSA). Most of the blood culture isolates from critically ill patients in intensive care unit were multidrug-resistant, ESBL producers and MRSA which raises a serious concern about the development of serious antibiotic resistance.<\/jats:p>","DOI":"10.1177\/0049475520977043","type":"journal-article","created":{"date-parts":[[2020,12,6]],"date-time":"2020-12-06T06:44:56Z","timestamp":1607237096000},"page":"44-48","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Bloodstream infections and antibiotic sensitivity pattern in intensive care unit"],"prefix":"10.1177","volume":"51","author":[{"given":"Parul","family":"Chaturvedi","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Microbiology, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamta","family":"Lamba","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Microbiology, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7612-3486","authenticated-orcid":false,"given":"Deepak","family":"Sharma","sequence":"additional","affiliation":[{"name":"Consultant Neonatologist, Department of Neonatology, National Institute of Medical and Sciences Medical College, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ved P","family":"Mamoria","sequence":"additional","affiliation":[{"name":"Head of department and Professor, Department of Microbiology, Mahatma Gandhi University of Medical Sciences and Technology, Jaipur, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,12,6]]},"reference":[{"key":"bibr1-0049475520977043","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-015-1056-x"},{"key":"bibr2-0049475520977043","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-05950-6"},{"key":"bibr3-0049475520977043","doi-asserted-by":"crossref","unstructured":"Gohel K, Jojera A, Soni S, Gang S, Sabnis R, Desai M. Bacteriological profile and drug resistance patterns of blood culture isolates in a tertiary care nephrourology teaching institute.\n                      Biomed Res Int\n                      2014; doi: 10.1155\/2014\/153747. Epub ahead of print 2014 Apr 7.","DOI":"10.1155\/2014\/153747"},{"key":"bibr4-0049475520977043","first-page":"2135","volume":"51","author":"Mahmood A","year":"2001","journal-title":"J Pak Med Assoc"},{"key":"bibr5-0049475520977043","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10071-23295"},{"key":"bibr6-0049475520977043","first-page":"25","volume":"16","author":"Simkhada P","year":"2016","journal-title":"Global J Med Res Part C: Microbiol Pathol"},{"key":"bibr7-0049475520977043","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.39.6.1211"},{"key":"bibr8-0049475520977043","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2018.03.030"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475520977043","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475520977043","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475520977043","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:32:58Z","timestamp":1777642378000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475520977043"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,6]]},"references-count":8,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1177\/0049475520977043"],"URL":"https:\/\/doi.org\/10.1177\/0049475520977043","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,6]]}}}