{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T07:13:18Z","timestamp":1785222798460,"version":"3.55.0"},"reference-count":8,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Idiopathic systemic capillary leak syndrome (ISCLS) is a potentially fatal disorder characterised by \u2018attacks\u2019 of varying intensity of hypovolemic shock in association with haemoconcentration and hypoalbuminaemia. It is a disease of exclusion, and the severity of attacks may mimic sepsis at presentation. We report a case of a lady with recurrent attacks of ISCLS with at least two life-threatening episodes, having been treated elsewhere as a case of steroid insufficiency. The diagnosis is often challenging, and treatment of an acute episode involves the judicious use of fluids and vasopressors, as required. Prophylaxis to prevent further attacks is of varied success.<\/jats:p>","DOI":"10.1177\/0049475520979299","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T03:24:30Z","timestamp":1608607470000},"page":"246-248","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Idiopathic systemic capillary leak syndrome \u2013 An often missed diagnosis"],"prefix":"10.1177","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4136-9843","authenticated-orcid":false,"given":"Remya","family":"Rajan","sequence":"first","affiliation":[{"name":"Senior PG Registrar, Department of Endocrinology and Metabolism, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9520-2072","authenticated-orcid":false,"given":"Nitin","family":"Kapoor","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Endocrinology and Metabolism, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hesarghatta S","family":"Asha","sequence":"additional","affiliation":[{"name":"Professor, Department of Endocrinology and Metabolism, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas V","family":"Paul","sequence":"additional","affiliation":[{"name":"Professor, Department of Endocrinology and Metabolism, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nihal","family":"Thomas","sequence":"additional","affiliation":[{"name":"Professor, Department of Endocrinology and Metabolism, Christian Medical College, Vellore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"bibr1-0049475520979299","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(60)90018-8"},{"key":"bibr2-0049475520979299","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2010.0159"},{"key":"bibr3-0049475520979299","doi-asserted-by":"publisher","DOI":"10.1378\/chest.120.4.1301"},{"key":"bibr4-0049475520979299","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-113-6-475"},{"key":"bibr5-0049475520979299","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1993.tb08195.x"},{"key":"bibr6-0049475520979299","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-2-201007200-00005"},{"key":"bibr7-0049475520979299","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(97)00272-6"},{"key":"bibr8-0049475520979299","doi-asserted-by":"publisher","DOI":"10.1586\/1744666X.2014.882771"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475520979299","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475520979299","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475520979299","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:32:59Z","timestamp":1777642379000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475520979299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,22]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1177\/0049475520979299"],"URL":"https:\/\/doi.org\/10.1177\/0049475520979299","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,22]]}}}