{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:03:58Z","timestamp":1787018638776,"version":"build-2736575974"},"reference-count":9,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,2,2]],"date-time":"2021-02-02T00:00:00Z","timestamp":1612224000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>\n                    Leptospirosis, a bacterial infection attributed to the group\n                    <jats:italic>leptospira<\/jats:italic>\n                    , remains a globally emerging public-health issue in many endemic tropical, subtropical and temperate zones of the world. The burden is expected to inflate with population shifts related to violent storms and urban floods leading to poor housing and inadequate sanitation. Leptospirosis may mimic other illnesses such as influenza, dengue fever, typhoid and malaria due to its myriad presentation ranging from a mild, self-limiting febrile illness to hepatorenal dysfunction, myocarditis, pulmonary haemorrhage, meningitis, optic neuritis and rhabdomyolysis. The classical gastrointestinal manifestation of leptospirosis without hepatorenal dysfunction (Weil\u2019s disease) is a rare entity. We report a rare presentation of concurrent appendicitis and rectal perforation in a patient, whose jaundice and thrombocytopenia led to a suspicion of leptospirosis, confirmed by serology and fulfilment of parameters under the modified Faine\u2019s criteria. The patient was managed successfully and discharged in a stable condition.\n                  <\/jats:p>","DOI":"10.1177\/0049475520981298","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T10:48:42Z","timestamp":1612954122000},"page":"427-431","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Jaundice and Thrombocytopenia in an acute abdomen with concurrent Appendicitis and spontaneous Rectal perforation: An unusual presentation of human leptospirosis"],"prefix":"10.1177","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9630-2932","authenticated-orcid":false,"given":"Deepak","family":"Rajput","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Surgery, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4847-4120","authenticated-orcid":false,"given":"Amit","family":"Gupta","sequence":"additional","affiliation":[{"name":"Additional Professor, Department of Surgery, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddharth Shankar","family":"Verma","sequence":"additional","affiliation":[{"name":"Junior Resident, Department of Surgery, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4546-0321","authenticated-orcid":false,"given":"Geetha Sindhuri","family":"Barabari","sequence":"additional","affiliation":[{"name":"Junior Resident, Department of Surgery, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajaz A","family":"Wani","sequence":"additional","affiliation":[{"name":"Consultant GI Oncology and HPB Surgery, SMVD Narayana Super Speciality Hospital, Katra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3397-1386","authenticated-orcid":false,"given":"Navin","family":"Kumar","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Surgery, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,2,2]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.64.748.163"},{"key":"e_1_3_3_3_2","first-page":"777","article-title":"Transplacental or congenital infection of leptospirosis. Clinical and experimental observations","volume":"82","author":"Chung HL","year":"1963","unstructured":"Chung HL, Ts\u2019ao WC, Mo PS, et al. Transplacental or congenital infection of leptospirosis. Clinical and experimental observations. Chin Med J 1963; 82: 777\u2013782.","journal-title":"Chin Med J"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1086\/340615"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/iep.12085"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3156.2009.02434.x"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1590\/s1678-9946201860023"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1999.61.731"},{"key":"e_1_3_3_9_2","unstructured":"Kumar SS. In: Indian guidelines for the diagnosis and management of human leptospirosis. In: A Muruganathan (ed). India: Medicine Update 2013 Chapter 7 pp. 23\u201329."},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00044-08"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475520981298","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0049475520981298","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0049475520981298","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:33:02Z","timestamp":1777642382000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0049475520981298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2,2]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1177\/0049475520981298"],"URL":"https:\/\/doi.org\/10.1177\/0049475520981298","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2,2]]}}}