{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T13:03:41Z","timestamp":1792069421294,"version":"4.4.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2021,5,6]],"date-time":"2021-05-06T00:00:00Z","timestamp":1620259200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>Pulmonary involvement is common in children with scrub typhus. Our paper outlines the clinical characteristics of pulmonary involvement and analyses the predictors of its severity. All scrub typhus serology-positive (optical density &gt;0.5) children with pulmonary symptoms were included. Of 506 serology-positive scrub typhus cases, 256 (50.5%) had pulmonary symptoms, of whom 50 (9.8%) were severe. These severe cases were compared with non-severe cases. Interstitial pneumonitis was the commonest chest radiographic finding. Logistic regression analysis identified \u2018fever clearance time\u2019 &gt;48\u2009h, facial puffiness, maculopapular rash and anaemia to be significantly associated with severe pulmonary involvement.<\/jats:p>","DOI":"10.1177\/00494755211012585","type":"journal-article","created":{"date-parts":[[2021,5,9]],"date-time":"2021-05-09T03:02:00Z","timestamp":1620529320000},"page":"382-386","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Clinical profile and predictors of severity in paediatric scrub typhus with pulmonary involvement"],"prefix":"10.1177","volume":"51","author":[{"given":"Dinesh Kumar","family":"Narayanasamy","sequence":"first","affiliation":[{"name":"Assistant Professor, Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Karaikal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1123-5270","authenticated-orcid":false,"given":"Thirunavukkarasu Arun","family":"Babu","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Pediatrics, All India Institute of Medical Sciences, Mangalagiri, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Mathiyalagen","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Community Medicine, Indira Gandhi Medical College and Research Institute, Pondicherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,5,6]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"Megan E Reller J and Dumler S. Scrub typhus (Orentiatsutsugamushi). In: Kliegman RM (ed.) Nelson textbook of paediatrics. Philadelphia: Elsevier 2016 p. 1504."},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-016-2171-6"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-018-2612-5"},{"key":"e_1_3_2_5_2","first-page":"387","article-title":"Scrub typhus in children at a tertiary hospital in north India: clinical profile and complications","volume":"24","author":"Kumar Bhat N","year":"2014","unstructured":"Kumar Bhat N, Dhar M, Mittal G, et al. Scrub typhus in children at a tertiary hospital in north India: clinical profile and complications. Iran J Pediatr 2014; 24: 387\u2013392.","journal-title":"Iran J Pediatr"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.184662"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2004.19.5.668"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.7883\/yoken.67.122"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1873-9598(10)70005-3"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir1065"},{"key":"e_1_3_2_11_2","volume-title":"Revised WHO classification and treatment of childhood pneumonia at health facilities. Implications for policy and implementation","author":"World Health Organization","year":"2014","unstructured":"World Health Organization. Revised WHO classification and treatment of childhood pneumonia at health facilities. Implications for policy and implementation, Geneva: World Health Organization, 2014."},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.15172\/pneu.2014.5\/482"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003064"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2010.149591"},{"key":"e_1_3_2_15_2","doi-asserted-by":"crossref","first-page":"693","DOI":"10.4103\/ijmr.IJMR_1888_15","article-title":"Eschar is associated with poor prognosis in scrub typhus","volume":"145","author":"Chauhan V","year":"2017","unstructured":"Chauhan V, Thakur A, Thakur S. Eschar is associated with poor prognosis in scrub typhus. Indian J Med Res 2017; 145: 693\u2013696.","journal-title":"Indian J Med Res"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13048"},{"key":"e_1_3_2_17_2","unstructured":"Squires JE and William F. Balistreri. Manifestation of liver diseases. In: Kliegman RM (ed.) Nelson textbook of paediatrics. Philadelphia: Elsevier 2016 p. 1922."},{"key":"e_1_3_2_18_2","doi-asserted-by":"crossref","unstructured":"Kim D Kim S Choi S Yun N. Clinical and laboratory findings associated with severe scrub typhus. BMC Infect Dis 2010; 10: 108.","DOI":"10.1186\/1471-2334-10-108"},{"key":"e_1_3_2_19_2","first-page":"167","article-title":"Clinical predictors of multiple organ dysfunction syndromes in pediatric patients with scrub typhus","volume":"63","author":"Zhao D","year":"2017","unstructured":"Zhao D, Zhang Y, Yin Z, et al. Clinical predictors of multiple organ dysfunction syndromes in pediatric patients with scrub typhus. J Trop Pediatr 2017; 63: 167\u2013173.","journal-title":"J Trop Pediatr"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpedi.1925.04120270019003"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(17)30448-5"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2466-10-15"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755211012585","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00494755211012585","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755211012585","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:33:18Z","timestamp":1777642398000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00494755211012585"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5,6]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1177\/00494755211012585"],"URL":"https:\/\/doi.org\/10.1177\/00494755211012585","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5,6]]}}}