{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T13:34:43Z","timestamp":1782826483847,"version":"3.54.5"},"reference-count":18,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T00:00:00Z","timestamp":1626393600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2021,10]]},"abstract":"<jats:p>This prospective, cross-sectional study, conducted from July 2018 to March 2019, aimed to determine the causes of constipation using high-resolution anorectal manometry. Among 33 children enrolled in the study, 31 (94%) children presented with complaints of constipation with mean duration of 2.3\u2009\u00b1\u20092.5 years and 12 (36.4%) children also had associated complaints of faecal incontinence with mean duration of 3.5\u2009\u00b1\u20092.8 years. Seven children (21.2%) had normal high-resolution anorectal manometry parameters; anal sphincter hypotonia with decreased squeeze in one child, anal sphincter hypertonia with other abnormal parameters were noted in 25 and absent recto-anal inhibitory reflex in two. The causes of constipation determined were functional constipation in 30 (91%) children, suspected Hirschsprung\u2019s disease in two and suspected dyssynergic defecatory disorder in one. Almost 90% had functional constipation of which anal hypotension and anal hypertension may be a part of chronic functional constipation.<\/jats:p>","DOI":"10.1177\/00494755211030362","type":"journal-article","created":{"date-parts":[[2021,7,16]],"date-time":"2021-07-16T12:24:25Z","timestamp":1626438265000},"page":"527-531","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Evaluation of constipation in children using high-resolution anorectal manometry"],"prefix":"10.1177","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4317-9288","authenticated-orcid":false,"given":"Vishrutha S","family":"Poojari","sequence":"first","affiliation":[{"name":"Fellow, Department of Pediatric Gastroenterology and Hepatology, BJ Wadia Hospital for Children, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonal","family":"Mirani","sequence":"additional","affiliation":[{"name":"Fellow, Department of Pediatric Gastroenterology and Hepatology, BJ Wadia Hospital for Children, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3600-126X","authenticated-orcid":false,"given":"Naman S","family":"Shetty","sequence":"additional","affiliation":[{"name":"Resident, Department of Pediatrics, BJ Wadia Hospital for Children, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ira","family":"Shah","sequence":"additional","affiliation":[{"name":"Head of the department, Department of Pediatric Gastroenterology and Hepatology, BJ Wadia Hospital for Children, Mumbai, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,7,16]]},"reference":[{"key":"bibr1-00494755211030362","unstructured":"Kuizenga WA and Benninga MA. Functional constipation and incontinence. In: Wyllie R, Hyams J and Kay M (ed)\n                      Pediatric gastrointestinal and liver disease\n                      . 5th ed. Alpharetta, GA: Elsevier, 2016, pp.124\u2013136."},{"key":"bibr2-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2010.12.010"},{"key":"bibr3-00494755211030362","doi-asserted-by":"crossref","unstructured":"Gupte S and Anderson RA. Constipation. In: Gupte S (ed)\n                      The short textbook of pediatrics\n                      . 11th ed. New Delhi, India: Jaypee, 2009, pp.472\u2013473.","DOI":"10.5005\/jp\/books\/10983"},{"key":"bibr4-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000266"},{"key":"bibr5-00494755211030362","doi-asserted-by":"publisher","DOI":"10.2147\/PHMT.S110940"},{"key":"bibr6-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12944"},{"key":"bibr7-00494755211030362","unstructured":"Rao SSC and Rattanakovit K. Anorectal disorders- Fecal Impaction, Descending Perineum Syndrome, Rectocele, and Levator Ani Syndrome. In: Rao SSC, Parkman HP and McCallum RW (eds)\n                      Handbook of gastrointestinal motility and functional disorders\n                      . West Deptford, NJ: SLACK Incorporated, 2015, pp. 279\u2013289."},{"key":"bibr8-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1097\/01.mpg.0000214164.90939.92"},{"key":"bibr9-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1097\/00005176-199911000-00029"},{"key":"bibr10-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.02.015"},{"key":"bibr11-00494755211030362","doi-asserted-by":"publisher","DOI":"10.5223\/pghn.2014.17.1.23"},{"key":"bibr12-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2009.01.008"},{"key":"bibr13-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2016.01.008"},{"key":"bibr14-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.13679"},{"key":"bibr15-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2982.2002.00347.x"},{"key":"bibr16-00494755211030362","unstructured":"Stendal C. Practical guide to gastrointestinal function testing, Malden, MA: Blackwell Science, 1997, pp. 247\u2013266."},{"key":"bibr17-00494755211030362","first-page":"204","volume":"22","author":"Tang PM","year":"2017","journal-title":"HK J Paediatr (new series)"},{"key":"bibr18-00494755211030362","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-020-00793-z"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755211030362","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00494755211030362","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755211030362","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:33:33Z","timestamp":1777642413000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00494755211030362"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,16]]},"references-count":18,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,10]]}},"alternative-id":["10.1177\/00494755211030362"],"URL":"https:\/\/doi.org\/10.1177\/00494755211030362","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,16]]}}}