{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T00:32:20Z","timestamp":1785371540396,"version":"3.55.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T00:00:00Z","timestamp":1630886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2022,1]]},"abstract":"<jats:p>Our was an observational follow-up study where the aim was to assess the baseline high-sensitivity C-reactive protein levels in 50 smear-positive pulmonary tuberculosis patients in association with socio-clinico-radiological profile and microbiological conversion. Smear and culture conversion of sputum samples at the end of intensive phase of anti-tubercular treatment were recorded. Baseline serum high-sensitivity C-reactive protein estimation was done by ELISA. Mean high-sensitivity C-reactive protein levels at baseline, smear\/culture converted and delayed converters were 68.1\u2009\u00b1\u200922.2\u2009mg\/l, 66.7\u2009\u00b1\u200922.0\u2009mg\/l and 91.6\u2009\u00b1\u20096.7\u2009mg\/l, respectively; high-sensitivity C-reactive protein levels were significantly higher in delayed converters as compared to sputum converters. Significantly higher baseline high-sensitivity C-reactive protein levels were seen in patients with bilateral chest X-ray lesions, cavitations, evening rise of temperature, haemoptysis and dyspnoea as compared to those without these features. high-sensitivity C-reactive protein, being a non-specific inflammatory marker could be an adjunct tool for TB prognosis.<\/jats:p>","DOI":"10.1177\/00494755211042127","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T04:28:42Z","timestamp":1630902522000},"page":"84-89","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Socio-clinico-radiological profile of smear-positive pulmonary tuberculosis patients in association with sputum conversion and baseline hsCRP levels"],"prefix":"10.1177","volume":"52","author":[{"given":"S Krishna","family":"Singha","sequence":"first","affiliation":[{"name":"Post Graduate Student, Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2471-4078","authenticated-orcid":false,"given":"Bineeta","family":"Kashyap","sequence":"additional","affiliation":[{"name":"Professor, Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajnish","family":"Avasthi","sequence":"additional","affiliation":[{"name":"Professor and Head, Department of Medicine, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Puneeta","family":"Hyanki","sequence":"additional","affiliation":[{"name":"CMO I\/C, DOTS Center, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NP","family":"Singh","sequence":"additional","affiliation":[{"name":"Director Professor and Head, Department of Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwani","family":"Khanna","sequence":"additional","affiliation":[{"name":"State TB Officer, Delhi RNTCP, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,9,6]]},"reference":[{"key":"bibr1-00494755211042127","unstructured":"World Health Organization.\n                      Global tuberculosis report 2019\n                      . 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