{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T01:53:25Z","timestamp":1780365205404,"version":"3.54.1"},"reference-count":26,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T00:00:00Z","timestamp":1657065600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2022,10]]},"abstract":"<jats:p>Hepatitis E virus (HEV) is recognized worldwide as the leading cause of orofecal-transmitted hepatitis. However, blood transmission has been increasingly implicated in recent years raising health concerns. In Algeria, updated prevalence data are lacking. We aimed to determine the prevalence of anti-HEV antibodies in the sera of volunteer blood donors from the Setif region in eastern Algeria. A total of 434 Samples were analyzed for anti-HEV IgG and IgM antibodies using an enzyme-linked immunosorbent assay (Wantai). Logistic regression modelling was used to identify associated risk factors. The IgG seroprevalence rate was 17.05%. Seven sera (0.16%) were weakly positive for IgM. No HEV RNA was detected. The IgG prevalence was significantly correlated with increasing age (p\u2009&lt;\u20091p.1000). Our data demonstrate a relatively high prevalence of anti-HEV IgG, indicating a possible risk of HEV blood transmission which requires vireamic seroprevalence studies to assess the real risk.<\/jats:p>","DOI":"10.1177\/00494755221112212","type":"journal-article","created":{"date-parts":[[2022,7,6]],"date-time":"2022-07-06T03:07:46Z","timestamp":1657076866000},"page":"479-483","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Seroprevalence of hepatitis E virus among blood donors in eastern Algeria"],"prefix":"10.1177","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6214-3328","authenticated-orcid":false,"given":"Houda","family":"Boukhrissa","sequence":"first","affiliation":[{"name":"Faculty of Medicine, Department of Infectious Diseases, University Ferhat Abbas Setif 1, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saleh","family":"Mechakra","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Infectious Diseases, University Ferhat Abbas Setif 1, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbes","family":"Mahnane","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Infectious Diseases, University Ferhat Abbas Setif 1, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadir","family":"Boussouf","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of epidemiology and preventive medicine, University of Constantine 3, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelkader","family":"Gasmi","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Infectious Diseases, University Ferhat Abbas Setif 1, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdelmadjid","family":"Lacheheb","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, Department of Infectious Diseases, University Ferhat Abbas Setif 1, Algeria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,7,6]]},"reference":[{"key":"bibr1-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1111\/tme.12405"},{"key":"bibr2-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1002\/hep.25505"},{"key":"bibr3-00494755221112212","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2017.00012"},{"key":"bibr4-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1111\/liv.13237"},{"key":"bibr5-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9838041"},{"key":"bibr6-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1159\/000357098"},{"key":"bibr7-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1937"},{"key":"bibr8-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00057-13"},{"key":"bibr9-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.02.050"},{"key":"bibr10-00494755221112212","doi-asserted-by":"publisher","DOI":"10.21037\/aob.2017.09.02"},{"key":"bibr11-00494755221112212","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-015-0807-5"},{"key":"bibr12-00494755221112212","unstructured":"Rubrique Monographie Wilaya.\n                      Agence Nationale d\u2019Interm\u00e9diation et de R\u00e9gulation Fonci\u00e8re Wilaya de SETIF\n                      2014; 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