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CB outperformed CS by detecting 7 missed cases and diagnosing 177 benign, 5 suspicious and 26 malignant cases compared to CS's 180 benign, 9 suspicious and 19 malignant cases. Using histopathology as a gold standard, CB showed a sensitivity of 96.4%, specificity of 98.3% and diagnostic accuracy of 98.1%, significantly higher than CS's 79.3% sensitivity, specificity of 97.7% and 95.2% accuracy. Using a 10% alcohol\u2013formalin method, CB also excelled in cytomorphological characterization, especially in background elements, cellularity and cellular architecture. CB offered improved diagnostic accuracy and allowed extra sections for additional tests. In resource-constrained settings, combining CS and CB enhances cytological assessment.<\/jats:p>","DOI":"10.1177\/00494755241260903","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T17:59:18Z","timestamp":1721757558000},"page":"346-351","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Cytomorphological comparison of alcohol\u2013formalin cell-block technique with conventional cytology in serous effusions in a low-resource setting"],"prefix":"10.1177","volume":"54","author":[{"given":"Neelam","family":"Kumari","sequence":"first","affiliation":[{"name":"Ex-Junior Resident, Department of Pathology, Dr. RPGMC, Tanda, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6427-6634","authenticated-orcid":false,"given":"Manupriya","family":"Sharma","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Pathology and Lab Medicine, AIIMS, Bilaspur (H.P), India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rashmi","family":"Kaul","sequence":"additional","affiliation":[{"name":"Professor and Head of Department, Department of Pathology, Dr. RPGMC, Tanda, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6333-2104","authenticated-orcid":false,"given":"Sujeet","family":"Raina","sequence":"additional","affiliation":[{"name":"Professor, Department of Medicine, Dr. RPGMC, Tanda (H.P), India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,7,23]]},"reference":[{"key":"bibr1-00494755241260903","doi-asserted-by":"publisher","DOI":"10.4103\/npmj.npmj_150_17"},{"key":"bibr2-00494755241260903","first-page":"43","volume":"11","author":"Li M","year":"2021","journal-title":"Am J Cancer Res"},{"key":"bibr3-00494755241260903","first-page":"773","volume":"35","author":"Wojcik EM","year":"1991","journal-title":"Acta Cytol"},{"key":"bibr4-00494755241260903","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.93210"},{"key":"bibr5-00494755241260903","first-page":"809","volume":"33","author":"Mair S","year":"1989","journal-title":"Acta Cytol"},{"key":"bibr6-00494755241260903","doi-asserted-by":"publisher","DOI":"10.4103\/cytojournal.cytojournal_20_19"},{"key":"bibr7-00494755241260903","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.39.1.114-d"},{"key":"bibr8-00494755241260903","first-page":"409","volume":"30","author":"Olson NJ","year":"1986","journal-title":"Acta Cytol"},{"key":"bibr9-00494755241260903","doi-asserted-by":"publisher","DOI":"10.1309\/G035-P2MM-D1TM-T5QE"},{"key":"bibr10-00494755241260903","first-page":"87","volume":"4","author":"Bansode S","year":"2015","journal-title":"Int J Sci Res"},{"key":"bibr11-00494755241260903","doi-asserted-by":"publisher","DOI":"10.4314\/ejhs.v24i2.4"},{"key":"bibr12-00494755241260903","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10716"},{"key":"bibr13-00494755241260903","first-page":"425","volume":"13","author":"Dey S","year":"2017","journal-title":"J Cancer Res Ther"},{"key":"bibr14-00494755241260903","doi-asserted-by":"publisher","DOI":"10.1159\/000495571"},{"key":"bibr15-00494755241260903","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2020.02.004"},{"key":"bibr16-00494755241260903","first-page":"329","volume":"36","author":"DiBonito L","year":"1992","journal-title":"Acta Cytol"},{"key":"bibr17-00494755241260903","doi-asserted-by":"publisher","DOI":"10.1159\/000484195"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755241260903","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00494755241260903","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755241260903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:36:27Z","timestamp":1777642587000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00494755241260903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,23]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1177\/00494755241260903"],"URL":"https:\/\/doi.org\/10.1177\/00494755241260903","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,23]]}}}