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We present the case of a 22-year-old Nigerian man with a 2-year history of multiple, dome-shaped papules and nodules on the skin with necrotic centres. General examination showed right axillary lymphadenopathy, non-pitting oedema, foot ulcer, and glove and stocking sensation loss. Despite previous misdiagnoses, histopathological examination showed dermal expansion by histiocytes arranged in a storiform pattern. Slit skin smear yielded abundant bacilli. The patient was started on WHO multidrug treatment, resulting in the improvement of his lesions. This case emphasises the importance of increased awareness of this rare presentation of leprosy.<\/jats:p>","DOI":"10.1177\/00494755241263615","type":"journal-article","created":{"date-parts":[[2024,7,23]],"date-time":"2024-07-23T18:02:20Z","timestamp":1721757740000},"page":"380-382","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["A case report of de novo histoid leprosy in a Nigerian male: A diagnostic dilemma"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7173-2589","authenticated-orcid":false,"given":"Chetanna Chioma","family":"Anaje","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chibuzo Ifeanyi","family":"Okpala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nkechi Anne","family":"Enechukwu","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4341-7685","authenticated-orcid":false,"given":"Felix Emeka","family":"Menkiti","sequence":"additional","affiliation":[{"name":"Department of Histopathology, NAUTH, Nnewi, Anambra State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ifeoma Florence","family":"Ezejiofor","sequence":"additional","affiliation":[{"name":"Department of Histopathology, NAUTH, Nnewi, Anambra State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chukwudi Christian","family":"Umenzekwe","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, NAUTH, Nnewi, Anambra State, Nigeria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,7,23]]},"reference":[{"key":"bibr1-00494755241263615","first-page":"129","volume":"31","author":"Wade HW","year":"1963","journal-title":"Int J Lepr"},{"key":"bibr2-00494755241263615","doi-asserted-by":"publisher","DOI":"10.4103\/ijdvl.IJDVL_475_17"},{"key":"bibr3-00494755241263615","first-page":"42","volume-title":"Nigerian Association of Dermatologists Conference abstract book","author":"Sadauki F","year":"2017"},{"key":"bibr4-00494755241263615","doi-asserted-by":"publisher","DOI":"10.1159\/000248566"},{"key":"bibr5-00494755241263615","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02540.x"},{"key":"bibr6-00494755241263615","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.1987.tb02993.x"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755241263615","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00494755241263615","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755241263615","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:36:28Z","timestamp":1777642588000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00494755241263615"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,23]]},"references-count":6,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,10]]}},"alternative-id":["10.1177\/00494755241263615"],"URL":"https:\/\/doi.org\/10.1177\/00494755241263615","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7,23]]}}}