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Despite supportive care, the patient progressed to severe hepatic encephalopathy and coagulopathy ensued. Management included N-acetylcysteine infusion, thromboelastography-guided transfusions and sedation with propofol. Persistent cholestatic jaundice was managed with ursodeoxycholic acid. The patient's condition gradually improved, highlighting the importance of tailored interventions for severe dengue liver complications.<\/jats:p>","DOI":"10.1177\/00494755251349897","type":"journal-article","created":{"date-parts":[[2025,6,26]],"date-time":"2025-06-26T04:40:28Z","timestamp":1750912828000},"page":"287-289","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Expanded dengue syndrome complicated by fulminant liver failure and prolonged intrahepatic cholestasis"],"prefix":"10.1177","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-4536-7449","authenticated-orcid":false,"given":"Pothumarthy","family":"Swathi Kiran","sequence":"first","affiliation":[{"name":"Senior Resident, Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5926-5885","authenticated-orcid":false,"given":"Praveen Kumar","family":"Tirlangi","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6399-1129","authenticated-orcid":false,"given":"Kavitha","family":"Saravu","sequence":"additional","affiliation":[{"name":"Professor and Head of the Unit, Department of Infectious Diseases, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,6,26]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"59","article-title":"Expanded dengue","volume":"64","author":"Kadam DB","year":"2016","unstructured":"Kadam DB, Salvi S, Chandanwale A. 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