{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T13:38:22Z","timestamp":1780493902040,"version":"3.54.1"},"reference-count":10,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T00:00:00Z","timestamp":1750377600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:p>Human adenovirus type 7 (HAdV-7) can cause severe, multisystem disease in children. Between November 2019 and February 2020, 28 children with confirmed HAdV-7 infection were admitted to our paediatric intensive care unit in South India. Most were under 5 years, and 86% required mechanical ventilation. Multisystem involvement included myocarditis (61%), CNS disease (32%), and haemophagocytosis (32%), with a high mortality rate (57%). Follow-up showed recurrent wheeze (33%) and bronchiectasis (16%) in survivors. This case series highlights the clinical characteristics, management strategies and outcome of a large HAdV-7 outbreak in a paediatric intensive care unit. Surveillance is essential to detect and prevent future adenovirus outbreaks in vulnerable paediatric populations.<\/jats:p>","DOI":"10.1177\/00494755251351520","type":"journal-article","created":{"date-parts":[[2025,6,20]],"date-time":"2025-06-20T04:03:02Z","timestamp":1750392182000},"page":"264-266","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Severe adenovirus type 7 infection in children: Case series from a paediatric intensive care unit in South India"],"prefix":"10.1177","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0665-5222","authenticated-orcid":false,"given":"Machinary Puthenpurayil","family":"Jayakrishnan","sequence":"first","affiliation":[{"name":"Government Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2446-4330","authenticated-orcid":false,"given":"Madona Devassikutty","family":"Fiji","sequence":"additional","affiliation":[{"name":"Government Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4389-7113","authenticated-orcid":false,"given":"Thekkile Gangadharan","family":"Sindhu","sequence":"additional","affiliation":[{"name":"Government Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0224-5656","authenticated-orcid":false,"given":"Vellani Thamunni","family":"Ajithkumar","sequence":"additional","affiliation":[{"name":"Government Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-1864-8360","authenticated-orcid":false,"given":"George","family":"Kalpana","sequence":"additional","affiliation":[{"name":"Government Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-1761-4721","authenticated-orcid":false,"given":"Balakrishnan","family":"Ajitha","sequence":"additional","affiliation":[{"name":"Government Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,6,20]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-022-00568-8"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2020.06.103"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0209720"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.21039"},{"key":"e_1_3_3_6_2","first-page":"434","article-title":"An outbreak of adenovirus type 7 infection in children in Montreal","volume":"108","author":"Brown RS","year":"1973","unstructured":"Brown RS, Nogrady MB, et al. An outbreak of adenovirus type 7 infection in children in Montreal. Can Med Assoc J 1973; 108: 434\u2013439.","journal-title":"Can Med Assoc J"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006454-199511000-00019"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2018.09.036"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.654002"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066620960687"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1080\/08880010390220162"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755251351520","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00494755251351520","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00494755251351520","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T13:37:11Z","timestamp":1777642631000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00494755251351520"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,20]]},"references-count":10,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["10.1177\/00494755251351520"],"URL":"https:\/\/doi.org\/10.1177\/00494755251351520","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,20]]}}}