{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:12:32Z","timestamp":1777907552381,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T00:00:00Z","timestamp":1752192000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2025,10]]},"abstract":"<jats:p>Lead toxicity remains a significant global public health concern, with diverse clinical manifestations influenced by the route and duration of exposure. The complexity of its presentation often makes timely diagnosis and intervention difficult. This case series presents two cases: a 35-year old male from rural Haryana, India, with environmental lead exposure resulting in cerebellar ataxia and microcytic anaemia, and a 30-year old battery factory worker with occupational exposure leading to motor neuropathy, nephropathy, and anaemia. These cases illustrate the diagnostic complexities associated with lead toxicity, particularly when serum lead levels do not reliably reflect the severity of exposure. The first case was linked to groundwater contamination, whereas the second case highlighted the impact of chronic workplace exposure despite apparently normal serum lead concentrations. Both cases demonstrated clinical improvement following exposure cessation and chelation therapy, emphasising the importance of early recognition and intervention. These case reports underscore the necessity of stringent environmental regulations, occupational safety measures, and heightened clinical awareness to mitigate lead-related morbidity.<\/jats:p>","DOI":"10.1177\/00494755251356758","type":"journal-article","created":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T08:39:47Z","timestamp":1752223187000},"page":"330-332","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["The silent threat: A case series on lead-induced neurological and systemic damage"],"prefix":"10.1177","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-9546-0394","authenticated-orcid":false,"given":"Rohit","family":"Sharma","sequence":"first","affiliation":[{"name":"Junior Resident, Department of Medicine, Pt. B. D. 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Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manish","family":"Kumar","sequence":"additional","affiliation":[{"name":"Senior Resident, Department of Medicine, Pt. B. D. Sharma Post Graduate Institute of Medical Sciences, Rohtak, Haryana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,11]]},"reference":[{"key":"e_1_3_2_2_2","volume-title":"Toxicological profile for lead","author":"Abadin H","unstructured":"Abadin H, Ashizawa A, Stevens Y-W, et al. Toxicological profile for lead. Atlanta (GA): Agency for Toxic Substances and Disease Registry (US), http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK158766\/ (2007, accessed 26 February 2025)."},{"key":"e_1_3_2_3_2","first-page":"501","article-title":"Heavy metal induced oxidative stress & its possible reversal by chelation therapy","volume":"128","author":"Flora SJS","year":"2008","unstructured":"Flora SJS, Mittal M, Mehta A. Heavy metal induced oxidative stress & its possible reversal by chelation therapy. Indian J Med Res 2008; 128: 501.","journal-title":"Indian J Med Res"},{"key":"e_1_3_2_4_2","first-page":"2","article-title":"Lead toxicity, a review of the literature. Part 1: exposure, evaluation, and treatment","volume":"11","author":"Patrick L","year":"2006","unstructured":"Patrick L. Lead toxicity, a review of the literature. Part 1: exposure, evaluation, and treatment. 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