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This ecological study analysed dengue incidence (1990\u20132021) and mortality (1980\u20132021) using global burden of disease data. Time series analysis, employing fast Fourier transform and harmonic regression, identified significant cyclical patterns. Dengue incidence and mortality exhibit marked cyclical behaviour, with regional periodicity ranging from \u223c17 to 30 years. These patterns suggest that long-term environmental and socio-epidemiological factors drive predictable waves of transmission and severity. 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