{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:12:22Z","timestamp":1777907542897,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T00:00:00Z","timestamp":1761696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    Our Multidrug-resistant tuberculosis poses a significant global health challenge, particularly in low- and middle-income countries where access to diagnostic and treatment services is limited.\n                    <jats:bold\/>\n                    Our multi-centre retrospective cohort study attempts to evaluate treatment outcomes and predictors of death or failure among 546 multi-drug-resistant tuberculosis patients,\n                    <jats:bold\/>\n                    <jats:bold\/>\n                    treated at eight specialised units between January 2017 and August 2018, with follow-up until June 2020. Overall, 69% achieved successful outcomes and 22.2% died. Significant predictors of death included older age, weight &lt;40\u2005kg, prior vitamin D use, and delayed sputum conversion.\n                    <jats:bold\/>\n                    Despite outcomes nearing World Health Organisation targets, older patients and those with prior second-line drug exposure require closer monitoring.\n                  <\/jats:p>","DOI":"10.1177\/00494755251389748","type":"journal-article","created":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T17:19:50Z","timestamp":1761758390000},"page":"71-76","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Multi-centre analysis of predictors of death and treatment failure among multi-drug-resistant tuberculosis patients in Pakistan"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6954-8766","authenticated-orcid":false,"given":"Abdul","family":"Wahid","sequence":"first","affiliation":[{"name":"Quaid-I-Azam University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qaiser","family":"Iqbal","sequence":"additional","affiliation":[{"name":"University of Balochistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amjad","family":"Khan","sequence":"additional","affiliation":[{"name":"Quaid-I-Azam University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asad","family":"Khan","sequence":"additional","affiliation":[{"name":"University of Balochistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faiz Ullah","family":"Khan","sequence":"additional","affiliation":[{"name":"CECOS University of Science and Technology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Farman Ullah","family":"Khan","sequence":"additional","affiliation":[{"name":"Capital University of Science and Technology"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,10,29]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"WHO. Third WHO consultation on the translation of tuberculosis research into global policy guidelines: meeting report April 4 2023. 2023. World Health Organization (WHO)."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(22)00359-7"},{"key":"e_1_3_3_4_2","unstructured":"WHO. Consolidated guidance on tuberculosis data generation and use. Module 1. Tuberculosis surveillance. 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