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The disease typically manifests in a biphasic nature; beginning with an incubation period ranging from several days to a few weeks, followed by a septicaemic phase, an interphase where symptoms resolve temporarily, and finally an immune phase. While most infections are mild, approximately 10% progress to severe disease involving multi-organ complications, typically manifesting during the immune phase. We report a case of myocarditis and septic shock during the acute phase of leptospirosis.<\/jats:p>","DOI":"10.1177\/00494755261454742","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T13:34:57Z","timestamp":1779802497000},"page":"770-772","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Myocarditis and septic shock as early manifestation of leptospirosis: Case report"],"prefix":"10.1177","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8998-3386","authenticated-orcid":false,"given":"Eunike Vania","family":"Christabel","sequence":"first","affiliation":[{"name":"Universitas Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahmi Adnan","family":"Musthofa","sequence":"additional","affiliation":[{"name":"Universitas Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reza","family":"Ferizal","sequence":"additional","affiliation":[{"name":"Universitas Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1530-5437","authenticated-orcid":false,"given":"Astari","family":"Ridhanya","sequence":"additional","affiliation":[{"name":"Universitas Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristo Benny P.","family":"Siahaan","sequence":"additional","affiliation":[{"name":"Universitas Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adeline Intan","family":"Pasaribu","sequence":"additional","affiliation":[{"name":"Universitas Indonesia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,26]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"678","article-title":"Diagnosis of leptospirosis utilizing modified Faine\u2019s criteria","volume":"52","author":"Shivakumar S","year":"2004","unstructured":"Shivakumar S, Shareek PS. Diagnosis of leptospirosis utilizing modified Faine\u2019s criteria. J Assoc Physicians India 2004; 52: 678\u2013679. PubMed PMID: 15847371.","journal-title":"J Assoc Physicians India"},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","unstructured":"Haake DA Levett PN. Leptospirosis in Humans. In. 2015. p. 65\u201397. doi:10.1007\/978-3-662-45059-8_5.","DOI":"10.1007\/978-3-662-45059-8_5"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.9.6022"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2018.00204"},{"key":"e_1_3_2_6_2","unstructured":"Guidelines for the control of leptospirosis. 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