{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T05:47:05Z","timestamp":1778305625065,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[1999,1,1]],"date-time":"1999-01-01T00:00:00Z","timestamp":915148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trop Doct"],"published-print":{"date-parts":[[1999,1]]},"abstract":"<jats:p>One hundred and ten adult patients hospitalized with dengue haemorrhagic fever (DHF) during the recent outbreak in North India were prospectively studied. Of these, 48 (43.6%) were grade 1, 40 (36.4%) grade II, 10 (9.1%) grade III and 12 (10.9%) grade IV DHF. Dengue shock syndrome (DSS) was seen in 22 (20%) patients. Fever, headache, myalgias and arthralgias were the common symptoms seen in 100%, 80.9%, 76.2% and 52.3% patients, respectively. Spontaneous bleeding was seen in 62 patients (56.4%) with mucocutaneous bleeding being the most common (46 patients). Gastrointestinal bleeding was seen in 38 (34.5%) patients. In as many as 40 patients, the haemorrhagic manifestations occurred after the fever had come down. Fifty-five patients (50%) required platelet transfusions. Twelve patients died, giving a mortality rate of 10.9% in the present study. Prompt recognition and supportive treatment can be lifesaving.<\/jats:p>","DOI":"10.1177\/004947559902900110","type":"journal-article","created":{"date-parts":[[2017,1,13]],"date-time":"2017-01-13T05:59:26Z","timestamp":1484287166000},"page":"27-30","source":"Crossref","is-referenced-by-count":32,"title":["Dengue Haemorrhagic Fever in Adults: A Prospective Study of 110 Cases"],"prefix":"10.1177","volume":"29","author":[{"given":"J P","family":"Wali","sequence":"first","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Biswas","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Handa","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P","family":"Aggarwal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Wig","sequence":"additional","affiliation":[{"name":"Department of Medicine, All India Institute of Medical Sciences, New Delhi 110 029, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S N","family":"Dwivedi","sequence":"additional","affiliation":[{"name":"Department of Bio-stastics, All India Institute of Medical Sciences, New Delhi 110 029, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1999,1,1]]},"reference":[{"key":"bibr1-004947559902900110","volume-title":"Viral Haemorrhagic Fevers","author":"World Health Organization","year":"1985"},{"key":"bibr2-004947559902900110","volume-title":"Dengue Haemorrhagic Fever: Diagnosis, Treatment and Control","author":"World Health Organization","year":"1986"},{"key":"bibr3-004947559902900110","first-page":"20","volume":"9","author":"Lal R","year":"1996","journal-title":"Natl Med J India"},{"key":"bibr4-004947559902900110","volume-title":"Handbook of Geographical and Historical Pathology","author":"Hirsch A","year":"1883"},{"key":"bibr5-004947559902900110","first-page":"243","volume":"59","author":"Smith GCE","year":"1956","journal-title":"J Trop Med Hyg"},{"key":"bibr6-004947559902900110","first-page":"636","volume":"21","author":"Halstead GB","year":"1990","journal-title":"SE Asian J Trop Med Public Health"},{"key":"bibr7-004947559902900110","doi-asserted-by":"publisher","DOI":"10.1126\/science.3277268"},{"key":"bibr8-004947559902900110","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1988.38.411"},{"key":"bibr9-004947559902900110","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1989.40.444"},{"key":"bibr10-004947559902900110","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1988.39.110"},{"key":"bibr11-004947559902900110","first-page":"189","volume":"49","author":"Ibrahim NM","year":"1995","journal-title":"Br J Clin Practice"},{"key":"bibr12-004947559902900110","first-page":"105","volume":"70","author":"Kabra SK","year":"1992","journal-title":"Bull WHO"},{"key":"bibr13-004947559902900110","doi-asserted-by":"publisher","DOI":"10.1007\/BF02015615"},{"key":"bibr14-004947559902900110","first-page":"111","volume":"92","author":"Tassniyom S","year":"1993","journal-title":"Pediatrics"}],"container-title":["Tropical Doctor"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/004947559902900110","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/004947559902900110","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T14:00:20Z","timestamp":1777644020000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/004947559902900110"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,1]]},"references-count":14,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,1]]}},"alternative-id":["10.1177\/004947559902900110"],"URL":"https:\/\/doi.org\/10.1177\/004947559902900110","relation":{},"ISSN":["0049-4755","1758-1133"],"issn-type":[{"value":"0049-4755","type":"print"},{"value":"1758-1133","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,1]]}}}