{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:50:40Z","timestamp":1791352240593,"version":"4.3.1"},"reference-count":15,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T00:00:00Z","timestamp":1760572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Psychiatry Med"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Generalized anxiety disorder (GAD) is a condition that causes persistent and excessive worry, leading to physical and emotional symptoms. Acupuncture, a traditional Chinese medicine practice, has been studied as a potential treatment for anxiety disorders, including GAD. Though acupuncture at HT-7 and GV-20 along with other acupuncture points reduce anxiety level, no study to our knowledge has examined the effect of acupuncture at HT-7 and GV-20 alone on GAD. Therefore, the purpose of this study was to examine the effect of needling at HT-7 (Shenmen) and GV-20 (Baihui) acupuncture points on anxiety levels and cardiovascular function in patients with GAD.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 60 participants ages 20-55 diagnosed with GAD were randomly assigned to either a study group or a control group. The study group received acupuncture at the HT-7 and GV-20 points, while the control group underwent breath awareness meditation in supine position. Both groups underwent 20\u00a0min of the practice daily for 10\u00a0days. Assessments included Hamilton Anxiety Rating Scale (HAM-A) score, blood pressure (BP) and pulse rate (PR), which were performed before and after the intervention.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Participants in the study group experienced a significant reduction in anxiety levels (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .001) compared to the control group. No significant inter-group differences were observed in systolic BP (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .686), diastolic BP (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .998), or PR (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = .925).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The present study suggests that needling at HT-7 and GV-20 acupuncture points (20\u00a0min\/session for 10\u00a0days) reduces anxiety levels without affecting cardiovascular function in younger and middle-aged patients with GAD.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/00912174251391031","type":"journal-article","created":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T23:47:12Z","timestamp":1760658432000},"page":"752-763","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Effect of Acupuncture at HT-7 (Shenmen) and GV-20 (Baihui) on Anxiety and Cardiovascular Functions in Generalized Anxiety Disorder: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"61","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0537-5058","authenticated-orcid":false,"given":"G.","family":"Dhanushya Devi","sequence":"first","affiliation":[{"name":"Government Yoga and Naturopathy Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Mooventhan","sequence":"additional","affiliation":[{"name":"Government Yoga and Naturopathy Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Nivethitha","sequence":"additional","affiliation":[{"name":"National Institute of Naturopathy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-7118-4147","authenticated-orcid":false,"given":"A.","family":"Vijay","sequence":"additional","affiliation":[{"name":"Government Yoga and Naturopathy Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Mangaiarkarasi","sequence":"additional","affiliation":[{"name":"Government Yoga and Naturopathy Medical College"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,16]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.21976"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.4103\/jimr.jimr_24_24"},{"key":"e_1_3_3_4_2","volume-title":"StatPearls","author":"Munir S","year":"2025","unstructured":"Munir S, Takov V. Generalized anxiety disorder. In: StatPearls. Treasure Island, FL: StatPearls Publishing; 2025."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1017\/S003329171200147X"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.4103\/indianjpsychiatry.indianjpsychiatry_824_23"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2023.1240489"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000030076"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12991-021-00327-5"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0165-0327(88)90072-9"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-024-03124-y"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2019.00014"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/267959"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joim.2024.06.004"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.2001.280.2.H628"}],"container-title":["The International Journal of Psychiatry in Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00912174251391031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/00912174251391031","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/00912174251391031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:08:02Z","timestamp":1791349682000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/00912174251391031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,16]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1177\/00912174251391031"],"URL":"https:\/\/doi.org\/10.1177\/00912174251391031","relation":{},"ISSN":["0091-2174","1541-3527"],"issn-type":[{"value":"0091-2174","type":"print"},{"value":"1541-3527","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,16]]}}}