{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,9]],"date-time":"2025-12-09T15:26:25Z","timestamp":1765293985378},"reference-count":17,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2013,3,8]],"date-time":"2013-03-08T00:00:00Z","timestamp":1362700800000},"content-version":"vor","delay-in-days":4418,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Journal of Clinical Pharma"],"published-print":{"date-parts":[[2001,2]]},"abstract":"<jats:p>The authors report a case of probable serotonin syndrome caused by the coadministration of sertraline and oxycodone. A 34 year\u2010old male patient experienced visual hallucinations and severe tremor after dramatically increasing his dosage of oxycodone while on stable amounts of sertraline and cyclosporin. Discontinuation of cyclosporin did not result in resolution of his symptoms. Consideration of a possible sertraline\u2010oxycodone interaction led to withholding sertraline, which resulted in symptom resolution. Serotonin syndrome has been noted with sertraline in combination with other drugs, but this is the first report in combination with a narcotic analgesic. Possible pharmacological mechanisms are discussed. In complicated patients that are taking multiple medications, physicians should be aware of this possible interaction to avoid delay in the diagnosis of serotonin syndrome.<\/jats:p>","DOI":"10.1177\/00912700122009926","type":"journal-article","created":{"date-parts":[[2003,7,19]],"date-time":"2003-07-19T09:38:13Z","timestamp":1058607493000},"page":"224-227","source":"Crossref","is-referenced-by-count":30,"title":["Visual Hallucination and Tremor Induced by Sertraline and Oxycodone in a Bone Marrow Transplant Patient"],"prefix":"10.1002","volume":"41","author":[{"given":"Curtis J.","family":"Rosebraugh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David A.","family":"Flockhart","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sally U.","family":"Yasuda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond L.","family":"Woosley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,3,8]]},"reference":[{"key":"e_1_2_1_2_2","first-page":"649","article-title":"Parkinsonism during cyclosporine treatment","volume":"18","author":"Wasserstein PH","year":"1996","journal-title":"Bone Marrow Transplantation"},{"key":"e_1_2_1_3_2","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199345060-00007"},{"key":"e_1_2_1_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0733-8619(18)30869-7"},{"issue":"11","key":"e_1_2_1_5_2","first-page":"1158","article-title":"Cortical blindness secondary to cyclosporine after orthotopic heart transplantation: a case report and review of the literature","volume":"15","author":"Drachman BM","year":"1996","journal-title":"J Heart Lung Transplant"},{"key":"e_1_2_1_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(84)91556-3"},{"key":"e_1_2_1_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198710013171404"},{"key":"e_1_2_1_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(82)92727-1"},{"key":"e_1_2_1_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-2999(97)01441-6"},{"key":"e_1_2_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(98)00057-2"},{"key":"e_1_2_1_11_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1468-2982.1996.1605323.x"},{"key":"e_1_2_1_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1744-6163.1994.tb00446.x"},{"issue":"2","key":"e_1_2_1_13_2","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1177\/106002809703100208","article-title":"Possible serotonin syndrome associated with tramadol and sertraline coadministration","volume":"31","author":"Mason BJ","year":"1997","journal-title":"Ann Pharmacother"},{"key":"e_1_2_1_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5846(98)00036-0"},{"issue":"1","key":"e_1_2_1_15_2","first-page":"481","article-title":"Alteration in regulation of serotonin release in rat dorsal raphe nucleus after prolonged exposure to morphine","volume":"286","author":"Tao R","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_2_1_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-8993(97)00103-0"},{"key":"e_1_2_1_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(95)00154-B"},{"key":"e_1_2_1_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199812000-00012"}],"container-title":["The Journal of Clinical Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1177%2F00912700122009926","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/accp1.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/00912700122009926","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,18]],"date-time":"2023-11-18T08:41:48Z","timestamp":1700296908000},"score":1,"resource":{"primary":{"URL":"https:\/\/accp1.onlinelibrary.wiley.com\/doi\/10.1177\/00912700122009926"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,2]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,2]]}},"alternative-id":["10.1177\/00912700122009926"],"URL":"https:\/\/doi.org\/10.1177\/00912700122009926","archive":["Portico"],"relation":{},"ISSN":["0091-2700","1552-4604"],"issn-type":[{"value":"0091-2700","type":"print"},{"value":"1552-4604","type":"electronic"}],"subject":[],"published":{"date-parts":[[2001,2]]}}}