{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T00:45:54Z","timestamp":1761007554815,"version":"build-2065373602"},"reference-count":0,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2004,6,1]],"date-time":"2004-06-01T00:00:00Z","timestamp":1086048000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nut in Clin Prac"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:p><jats:italic>Background:<\/jats:italic> Who benefits from parenteral nutrition (PN) has been the subject of much debate and 4 recent meta\u2010analyses. <jats:italic>Methods:<\/jats:italic> We reviewed the 4 meta\u2010analyses that examined the prospective, randomized, clinical trials (PRCT) that compared PN with no nutrition support (standard care) for design, study population, outcomes evaluated, and results. <jats:italic>Results:<\/jats:italic> Overall, a total of 113 PRCT were included in the 4 meta\u2010analyses; however, only 4 studies were included in all of them. Despite the differences in populations studied and outcomes evaluated, some similarities emerged: (1) PN does not affect mortality; (2) PN does not reduce complications in normally nourished patients; (3) in malnourished patients, PN demonstrated a trend for reduced infections and complication rates; and (4) PN reduced postoperative complications in patients having surgery for cancer of the esophagus or stomach. <jats:italic>Conclusion:<\/jats:italic> PN does not appear to be beneficial for most hospitalized patients. Among those with malnutrition or with upper gastrointestinal cancer, benefits may exist; however, these were influenced by quality of the study and year of publication.<\/jats:p>","DOI":"10.1177\/0115426504019003255","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:23:41Z","timestamp":1210793021000},"page":"255-262","source":"Crossref","is-referenced-by-count":7,"title":["Indications for Administration of Parenteral Nutrition in Adults"],"prefix":"10.1002","volume":"19","author":[{"given":"Carol","family":"Braunschweig","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"HuiFang","family":"Liang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Sheean","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,6]]},"container-title":["Nutrition in Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0115426504019003255","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T13:57:02Z","timestamp":1760968622000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0115426504019003255"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1177\/0115426504019003255"],"URL":"https:\/\/doi.org\/10.1177\/0115426504019003255","archive":["Portico"],"relation":{},"ISSN":["0884-5336","1941-2452"],"issn-type":[{"type":"print","value":"0884-5336"},{"type":"electronic","value":"1941-2452"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}