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The absence of burned tissue can dampen fluid requirements and metabolic needs of toxic epidermal necrolysis in comparison to equivalent burn injury. In the following case report, a 69\u2010year\u2010old woman with multiple medical problems developed toxic epidermal necrolysis after treatment with metolazone and phenytoin. Her measured energy expenditure (3360 kcal) was considerably higher than previously reported caloric expenditure in toxic epidermal necrolysis patients (2500 kcal).<\/jats:p>","DOI":"10.1177\/011542659100600118","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:23:41Z","timestamp":1210793021000},"page":"18-20","source":"Crossref","is-referenced-by-count":7,"title":["Toxic Epidermal Necrolysis"],"prefix":"10.1002","volume":"6","author":[{"given":"Joseph A.","family":"Lacy","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1991,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1956.tb12766.x"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0190-9622(88)80254-8"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(89)80736-X"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1987.01660330064009"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1988.01670050100031"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"2207","DOI":"10.1001\/jama.1987.03390160093035","article-title":"Burn treatment for the unburned","volume":"257","author":"Pruitt BA","year":"1987","journal-title":"J Am Med Assoc"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"2171","DOI":"10.1001\/jama.1987.03390160057026","article-title":"Toxic epidermal necrolysis. 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