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Free radicals are normally neutralized by efficient systems in the body that include the antioxidant enzymes (superoxide dismutase, catalase, and glutathione peroxidase) and the nutrient\u2010derived antioxidant small molecules (vitamin E, vitamin C, carotenes, flavonoids, glutathione, uric acid, and taurine). In healthy individuals, a delicate balance exists between free radicals and antioxidants. In some pathologic conditions such as diabetes, and in critically ill patients, oxidative stress causes the level of antioxidants to fall below normal. Antioxidant supplements for such conditions are expected to be of benefit. As a preventive measure against certain diseases, the best approach for healthy individuals is to regularly consume adequate amounts of antioxidant\u2010rich foods, eg, fruits and vegetables.<\/jats:p>","DOI":"10.1177\/011542659501000119","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:23:41Z","timestamp":1210793021000},"page":"19-25","source":"Crossref","is-referenced-by-count":102,"title":["Role of Antioxidants in Health Maintenance"],"prefix":"10.1002","volume":"10","author":[{"given":"Vishwanath M.","family":"Sardesai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1995,2]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1096\/fasebj.7.12.8375611","article-title":"Biology of free radical scavengers: an evaluation of ascorbate","volume":"7","author":"Rose RC","year":"1993","journal-title":"FASEB 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