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Six infants with ONH are presented; cerebral abnormalities were demonstrated by cranial ultrasound in five. Neonatal cholestatic jaundice and hypoglycaemia occurred in one infant. Two died and represent a group likely to remain undetected unless routine ophthalmic examination of neurologically abnormal neonates is undertaken. In infancy, both ocular and systemic aspects of ONH can be investigated simply and without sedation.<\/jats:p>","DOI":"10.1177\/014107688607900109","type":"journal-article","created":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T23:36:54Z","timestamp":1484264214000},"page":"25-29","source":"Crossref","is-referenced-by-count":4,"title":["Optic Nerve Hypoplasia in Infancy"],"prefix":"10.1177","volume":"79","author":[{"given":"A R","family":"Fielder","sequence":"first","affiliation":[{"name":"Departments of Ophthalmology and Child Health, University of Leicester Medical School, Leicester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M I","family":"Levene","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology and Child Health, University of Leicester Medical School, Leicester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J Q","family":"Trounce","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology and Child Health, University of Leicester Medical School, Leicester"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M S","family":"Tanner","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology and Child Health, University of Leicester Medical School, Leicester"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,1,1]]},"reference":[{"key":"bibr-bibr1-014107688607900109","first-page":"425","volume":"79","author":"Acers TE.","year":"1981","journal-title":"Trans Am Ophthalmol Soc"},{"key":"bibr-bibr2-014107688607900109","unstructured":"Brown G, Tasman W. 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