{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:14:27Z","timestamp":1777864467416,"version":"3.51.4"},"reference-count":12,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[1986,7,1]],"date-time":"1986-07-01T00:00:00Z","timestamp":520560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J R Soc Med"],"published-print":{"date-parts":[[1986,7]]},"abstract":"<jats:p>A study was performed to determine the morbidity and mortality from ischaemic heart disease (IHD) in patients with heterozygous familial hypercholesterolaemia (FH) and severe hypertriglyceridaemia (pretreatment plasma triglyceride &gt; 5 mmol\/l). Twenty-nine (38%) of 76 patients with FH and 8 (44%) of 18 patients with hypertriglyceridaemia had evidence of IHD. Over a mean follow-up period of 5.5 years, 2 patients with hypertriglyceridaemia died but there were no deaths in patients with FH. This contrasts with earlier reports which showed a high mortality in FH patients. The lower mortality may be due to improved treatment and consequent lower levels of cholesterol.<\/jats:p>","DOI":"10.1177\/014107688607900705","type":"journal-article","created":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T19:56:34Z","timestamp":1484250994000},"page":"391-394","source":"Crossref","is-referenced-by-count":0,"title":["Cardiovascular Risk in Patients with Treated Familial Hypercholesterolaemia and Patients with Severe Hypertriglyceridaemia"],"prefix":"10.1177","volume":"79","author":[{"given":"BPJ","family":"Way","sequence":"first","affiliation":[{"name":"Department of Cardiology and Lipid Clinic, John Radcliffe Hospital, Oxford; and Department of Community Medicine and General Practice, Radcliffe Infirmary, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M J","family":"Ball","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Lipid Clinic, John Radcliffe Hospital, Oxford; and Department of Community Medicine and General Practice, Radcliffe Infirmary, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M","family":"Thorogood","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Lipid Clinic, John Radcliffe Hospital, Oxford; and Department of Community Medicine and General Practice, Radcliffe Infirmary, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S M","family":"Cobbe","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Lipid Clinic, John Radcliffe Hospital, Oxford; and Department of Community Medicine and General Practice, Radcliffe Infirmary, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J I","family":"Mann","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Lipid Clinic, John Radcliffe Hospital, Oxford; and Department of Community Medicine and General Practice, Radcliffe Infirmary, Oxford"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1986,7,1]]},"reference":[{"key":"bibr-bibr1-014107688607900705","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-74-1-1"},{"key":"bibr-bibr2-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.45.4.815"},{"key":"bibr-bibr3-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(81)91338-6"},{"key":"bibr-bibr4-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340270029025"},{"key":"bibr-bibr5-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1984.03340270043026"},{"key":"bibr-bibr6-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(69)90930-1"},{"key":"bibr-bibr7-014107688607900705","volume-title":"Cardiovascular survey methods","author":"Rose GA","year":"1982","edition":"2"},{"key":"bibr-bibr8-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(76)90090-5"},{"key":"bibr-bibr9-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)42943-8"},{"key":"bibr-bibr10-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.36.1.77"},{"key":"bibr-bibr11-014107688607900705","doi-asserted-by":"publisher","DOI":"10.1111\/j.0954-6820.1975.tb19536.x"},{"key":"bibr-bibr12-014107688607900705","first-page":"103","volume":"271","author":"McCormick JS","year":"1985","journal-title":"J R Coll Gen Pract"}],"container-title":["Journal of the Royal Society of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107688607900705","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107688607900705","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:42:23Z","timestamp":1777527743000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/014107688607900705"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,7]]},"references-count":12,"journal-issue":{"issue":"7","published-print":{"date-parts":[[1986,7]]}},"alternative-id":["10.1177\/014107688607900705"],"URL":"https:\/\/doi.org\/10.1177\/014107688607900705","relation":{},"ISSN":["0141-0768","1758-1095"],"issn-type":[{"value":"0141-0768","type":"print"},{"value":"1758-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,7]]}}}