{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T23:39:35Z","timestamp":1778629175242,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[1987,5,1]],"date-time":"1987-05-01T00:00:00Z","timestamp":546825600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J R Soc Med"],"published-print":{"date-parts":[[1987,5]]},"abstract":"<jats:p>The effect of unprocessed bran in a dose of 5 g three times daily and a dose of 2.5 g three times daily for one year on the recurrence rate of anal fissures was studied in a double-blind, placebo-controlled trial in 90 patients with recently healed acute posterior anal fissures. Fifteen patients (16.6%) were withdrawn before the code was broken due to failure to follow the trial protocol for various reasons. Significantly fewer recurrences occurred in patients receiving bran 5 g throe times daily (recurrence rate 16%, 95% confidence limits, 4.54 to 36.08) when compared with patients receiving bran 2.5 g three times daily (60%; 38.67 to 78.87) ( P&lt;0.01) and with patients receiving placebo three times daily (68%; 46.50 to 85.05) ( P&lt;0.01). No significant difference in recurrences was found between patients on bran 2.5 g and those on placebo.<\/jats:p>","DOI":"10.1177\/014107688708000513","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T01:05:58Z","timestamp":1520471158000},"page":"296-298","source":"Crossref","is-referenced-by-count":78,"title":["Maintenance Therapy with Unprocessed Bran in the Prevention of Acute Anal Fissure Recurrence"],"prefix":"10.1177","volume":"80","author":[{"given":"S L","family":"Jensen","sequence":"first","affiliation":[{"name":"General Practice and Surgical Clinic, Laegehuset, R\u00f8nnebaer All\u00e9, Elsinore, and Department of Surgical Gastroenterology, Rigshospitalet, University of Copenhagen, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,5,1]]},"reference":[{"key":"bibr1-014107688708000513","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.292.6529.1167"},{"key":"bibr2-014107688708000513","volume-title":"Surgery of anus, rectum, and colon.","author":"Goligher J.C.","year":"1984","edition":"4"},{"key":"bibr3-014107688708000513","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.289.6444.528"},{"key":"bibr4-014107688708000513","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6016.988"},{"key":"bibr5-014107688708000513","doi-asserted-by":"publisher","DOI":"10.1007\/BF02553653"},{"key":"bibr6-014107688708000513","first-page":"131","author":"Painter N.S.","year":"1972","journal-title":"Br Med J"},{"key":"bibr7-014107688708000513","author":"Jensen S.L.","journal-title":"Dis Colon Rectum"}],"container-title":["Journal of the Royal Society of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107688708000513","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107688708000513","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:37:35Z","timestamp":1777527455000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/014107688708000513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1987,5]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1987,5]]}},"alternative-id":["10.1177\/014107688708000513"],"URL":"https:\/\/doi.org\/10.1177\/014107688708000513","relation":{},"ISSN":["0141-0768","1758-1095"],"issn-type":[{"value":"0141-0768","type":"print"},{"value":"1758-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[1987,5]]}}}