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Heart rate, blood pressure, respiratory rate, peak flow and minute volume were measured over a three-hour study period. Except for a slight fall in systolic blood pressure in the nalbuphine-treated group, there were no statistically significant differences between the groups. The nalbuphine-treated group had higher levels of aspartate aminotransferase and hydroxybutyric acid dehydrogenase but not creatine phosphokinase. The haemodynamic outcome and mortality at three months of the two groups were similar. It is concluded that nalbuphine provides effective analgesia coupled with few adverse circulatory or respiratory effects.<\/jats:p>","DOI":"10.1177\/014107688708000708","type":"journal-article","created":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T21:13:15Z","timestamp":1484255595000},"page":"418-421","source":"Crossref","is-referenced-by-count":6,"title":["Experience with Nalbuphine, a New Opioid Analgesic, in Acute Myocardial Infarction"],"prefix":"10.1177","volume":"80","author":[{"given":"R A","family":"Greenbaum","sequence":"first","affiliation":[{"name":"Royal Free Hospital and School of Medicine, London NW3"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G","family":"Kaye","sequence":"additional","affiliation":[{"name":"Hackney Hospital, London E9"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P D","family":"Mason","sequence":"additional","affiliation":[{"name":"Ealing Hospital, Southall, Middlesex"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1987,7,1]]},"reference":[{"key":"bibr-bibr1-014107688708000708","first-page":"393","volume-title":"Clinical pharmacology","author":"Laurence DR","year":"1980","edition":"5"},{"key":"bibr-bibr2-014107688708000708","first-page":"13.174","volume-title":"Oxford textbook of medicine","author":"Pentecost BL","year":"1983"},{"key":"bibr-bibr3-014107688708000708","first-page":"1301","volume-title":"Heart disease \u2014 a textbook of cardiovascular medicine","author":"Sobel BE","year":"1984"},{"key":"bibr-bibr4-014107688708000708","unstructured":"Public Health in Europe. 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