{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:10:00Z","timestamp":1777864200577,"version":"3.51.4"},"reference-count":3,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[1989,12,1]],"date-time":"1989-12-01T00:00:00Z","timestamp":628473600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J R Soc Med"],"published-print":{"date-parts":[[1989,12]]},"abstract":"<jats:p>In patients with acute adrenocortical insufficiency prompt recognition and treatment may be life-saving. Treatment should be initiated immediately before confirmation of the diagnosis. As shown by these case reports, junior staff on acute medical and surgical services, to whom these patients usually first present, may not appreciate that (a) hyponatraemia and hyperkalaemia, in the absence of renal failure, should immediately suggest the diagnosis of adrenal insufficiency and (b) treatment should precede confirmation of the diagnosis. Attempts to correct hyperkalaemia due to adrenocortical insufficiency with insulin and infusions of dextrose is inappropriate and potentially dangerous but seems to be a not unusual mistake.<\/jats:p>","DOI":"10.1177\/014107688908201214","type":"journal-article","created":{"date-parts":[[2018,3,8]],"date-time":"2018-03-08T01:17:57Z","timestamp":1520471877000},"page":"741-742","source":"Crossref","is-referenced-by-count":7,"title":["Pitfalls in the Management of Acute Adrenocortical Insufficiency: Discussion Paper"],"prefix":"10.1177","volume":"82","author":[{"given":"A","family":"Waise","sequence":"first","affiliation":[{"name":"Departments of Clinical Biochemistry and Medicine, Hope Hospital, University of Manchester School of Medicine, Eccles Old Road, Salford M6 8HD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R J","family":"Young","sequence":"additional","affiliation":[{"name":"Departments of Clinical Biochemistry and Medicine, Hope Hospital, University of Manchester School of Medicine, Eccles Old Road, Salford M6 8HD"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1989,12,1]]},"reference":[{"key":"bibr1-014107688908201214","first-page":"1753","volume-title":"Harrison's principles of internal medicine.","author":"Williams G.H.","year":"1987"},{"key":"bibr2-014107688908201214","first-page":"455","volume":"11","author":"Hall R.","year":"1984","journal-title":"Med Int"},{"key":"bibr3-014107688908201214","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-595X(85)80084-0"}],"container-title":["Journal of the Royal Society of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107688908201214","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107688908201214","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:38:09Z","timestamp":1777527489000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/014107688908201214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1989,12]]},"references-count":3,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1989,12]]}},"alternative-id":["10.1177\/014107688908201214"],"URL":"https:\/\/doi.org\/10.1177\/014107688908201214","relation":{},"ISSN":["0141-0768","1758-1095"],"issn-type":[{"value":"0141-0768","type":"print"},{"value":"1758-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[1989,12]]}}}