{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T03:12:18Z","timestamp":1777864338574,"version":"3.51.4"},"reference-count":6,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1991,3,1]],"date-time":"1991-03-01T00:00:00Z","timestamp":667785600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J R Soc Med"],"published-print":{"date-parts":[[1991,3]]},"abstract":"<jats:p>A consecutive series of 35 clinically non-secretory pituitary adenomas treated surgically by the trans-ethmoidal approach is presented. Mean age at presentation was 60 years, with a male-to-female ratio of 2:1. These tumours present later than hormone secreting tumours: 90% were over 2 cm in diameter at operation. Seventy-one per cent of patients had impaired vision and 89% had hypopituitarism. Surgical treatment relieved or significantly improved visual fields in 79% of patients with impaired vision. Ninety-one per cent required permanent hormone replacement. Mean follow-up was for 4.4 years. Five tumours recurred, causing recurrent visual symptoms. No tumours recurred in those patients treated with postoperative radiotherapy, but follow-up in this group was only for a mean of 2.7 years.<\/jats:p>","DOI":"10.1177\/014107689108400308","type":"journal-article","created":{"date-parts":[[2018,2,28]],"date-time":"2018-02-28T02:21:48Z","timestamp":1519784508000},"page":"140-143","source":"Crossref","is-referenced-by-count":16,"title":["Non-Secretory Adenomas of the Pituitary Treated by Trans-Ethmoidal Sellotomy"],"prefix":"10.1177","volume":"84","author":[{"given":"G R","family":"Shone","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S H","family":"Richards","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M D","family":"Hourihan","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R","family":"Hall","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J P","family":"Thomas","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M F","family":"Scanlon","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, University Hospital of Wales, Heath Park, Cardiff CF4 4XW"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1991,3,1]]},"reference":[{"key":"bibr1-014107689108400308","first-page":"367","volume-title":"Pathological aspects in clinical neuroendocrinology: a patho-physiological approach.","author":"Kovacs K.","year":"1979"},{"key":"bibr2-014107689108400308","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8529(18)30474-2"},{"key":"bibr3-014107689108400308","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6508.1547"},{"key":"bibr4-014107689108400308","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1986.64.5.0713"},{"key":"bibr5-014107689108400308","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.1987.tb00809.x"},{"key":"bibr6-014107689108400308","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-62-6-1173"}],"container-title":["Journal of the Royal Society of Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107689108400308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014107689108400308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T05:40:15Z","timestamp":1777527615000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/014107689108400308"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1991,3]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1991,3]]}},"alternative-id":["10.1177\/014107689108400308"],"URL":"https:\/\/doi.org\/10.1177\/014107689108400308","relation":{},"ISSN":["0141-0768","1758-1095"],"issn-type":[{"value":"0141-0768","type":"print"},{"value":"1758-1095","type":"electronic"}],"subject":[],"published":{"date-parts":[[1991,3]]}}}