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After that, method of feedback linearization is put forward for fractional-order nonlinear systems, and then applied to design observer based controller for an artificial pancreas for a patient with diabetes. Using FOTF toolbox in MATLAB, the designed controller, observer, and the system are simulated. Using simulation results, it is shown that the designed controller and observer are stable, and the desired level of glucose concentration is being tracked faithfully.<\/jats:p>","DOI":"10.1177\/0142331220911584","type":"journal-article","created":{"date-parts":[[2020,4,21]],"date-time":"2020-04-21T05:48:12Z","timestamp":1587448092000},"page":"2372-2381","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Controller design for a fractional-order nonlinear glucose-insulin system using feedback linearization"],"prefix":"10.1177","volume":"42","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7532-0103","authenticated-orcid":false,"given":"Muhammad Waleed","family":"Khan","sequence":"first","affiliation":[{"name":"Department of Electrical Engineering, Pakistan Institute of Engineering and Applied Sciences, Pakistan"},{"name":"Department of Computer and Information Sciences, Pakistan Institute of Engineering 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