{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T11:51:13Z","timestamp":1792324273356,"version":"4.4.0"},"reference-count":49,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2003,10,1]],"date-time":"2003-10-01T00:00:00Z","timestamp":1064966400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behav Modif"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:p>\n                    Idiopathic hyperventilation has been defined as a respiratory-related psychophysiological complaint. This study attempted to clarify relationships between psychological and physiological variables in this condition. Participants demonstrated increased anxiety, depression, and symptoms consistent with hyperventilation. This was associated with a reduced peripheral chemosensitivity (isocapnic hypoxic rebreathe; -0.84 \u00b1 0.5 min\n                    <jats:sup>-1<\/jats:sup>\n                    *%O\n                    <jats:sub>2<\/jats:sub>\n                    <jats:sup>-1<\/jats:sup>\n                    ), which was normalized with experimentally increased pCO\n                    <jats:sub>2<\/jats:sub>\n                    . Resting CO\n                    <jats:sub>2<\/jats:sub>\n                    sensitivity was close to normal (2.1 \u00b1 1.0 min\n                    <jats:sup>-1<\/jats:sup>\n                    * mmHg\n                    <jats:sup>-1<\/jats:sup>\n                    ). Breath hold time was significantly reduced versus controls (20.4s\u00b112svs.63s\u00b131s), and resting P\n                    <jats:sub>ET<\/jats:sub>\n                    CO\n                    <jats:sub>2<\/jats:sub>\n                    was correlated with the anxiety score. Also, the ventilatory response to moderate intensity exercise was augmented (vs. controls). The normalcy of pulmonary and chemoreceptor responses suggests that psychological factors may initiate this hyperventilation, which may become a conditioned response with an increased drive to breathe.\n                  <\/jats:p>","DOI":"10.1177\/0145445503256318","type":"journal-article","created":{"date-parts":[[2003,9,20]],"date-time":"2003-09-20T04:25:16Z","timestamp":1064031916000},"page":"637-652","source":"Crossref","is-referenced-by-count":24,"title":["Behavioral Influences and Physiological Indices of Ventilatory Control in Subjects with Idiopathic Hyperventilation"],"prefix":"10.1177","volume":"27","author":[{"given":"Sandy","family":"Jack","sequence":"first","affiliation":[{"name":"Aintree Chest Centre, University Hospital Aintree"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry B.","family":"Rossiter","sequence":"additional","affiliation":[{"name":"University of California, San Diego"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher J.","family":"Warburton","sequence":"additional","affiliation":[{"name":"Aintree Chest Centre, University Hospital Aintree"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Whipp","sequence":"additional","affiliation":[{"name":"Division of Respiratory and Critical Care Physiology and Medicine, Harbor-UCLA Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2003,10,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(70)90062-8"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.152.5.698"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1986.60.6.2020"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1016\/0167-8760(94)90027-2"},{"key":"atypb5","unstructured":"Dick, T. E., Orem, J. M. & Shea, S. A. (1997). Behavioural control of breathing. In R. G. Crystal, J. R. West, E. R. Weibel, & P. J. Barnes (Eds.), The Lung Scientific Foundation (pp. 1821-1837). Philadelphia: Lippincott-Raven."},{"key":"atypb6","doi-asserted-by":"crossref","unstructured":"Dudley, D. L. & Pitts-Poarch, A. R. (1980). Psychological aspects of respiratory control. Clinics in Chest Medicine, 1, 131-143.","DOI":"10.1016\/S0272-5231(21)00058-7"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1991.70.2.676"},{"key":"atypb8","doi-asserted-by":"crossref","unstructured":"Hirshman, C. A., McCullough, R. E. & Weil, J. V. (1975). Normal values for hypoxic and hypercapnic ventilatory drives in man. Journal of Applied Physiology, 38, 1075-1098.","DOI":"10.1152\/jappl.1975.38.6.1095"},{"key":"atypb9","doi-asserted-by":"crossref","unstructured":"Homma, I., Kanamaru, A. & Masaoka, Y. (2001). Location and electric current sources of breathlessness in the human brain. In Y. 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