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A head and neck computed tomography scan with contrast medium showed an irregular, soft-tissue-like, irregularly enhanced lesion of the base of the tongue extending to its posterolateral portion. The tumor reached the lateral wall of the oropharynx, which showed a nonhomogeneous aspect. The patient underwent resection of the tumor via a conservative transmandibular approach. A clear cell adenocarcinoma of the base of the tongue is rarely a primary malignant lesion; it is more frequently a secondary lesion from a metastatic renal tumor. Because of this neoplasm's relatively slow growth rate and low incidence of metastasis or local recurrence, the gold standard of treatment is complete excision of the tumor with a sufficient tumor-free margin.<\/jats:p>","DOI":"10.1177\/014556131109000512","type":"journal-article","created":{"date-parts":[[2019,1,10]],"date-time":"2019-01-10T03:19:07Z","timestamp":1547090347000},"page":"E9-E16","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Clear Cell Adenocarcinoma of the Base of the Tongue: A Case Report and Review of the Literature"],"prefix":"10.1177","volume":"90","author":[{"given":"Augusto Pietro","family":"Casani","sequence":"first","affiliation":[{"name":"Department of Neuroscience, University of Pisa, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuela","family":"Marchetti","sequence":"additional","affiliation":[{"name":"Department of Neuroscience, University of 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