{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,30]],"date-time":"2026-06-30T23:05:12Z","timestamp":1782860712117,"version":"3.54.5"},"reference-count":10,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>Postoperative chylous fistula after neck dissection is an uncommon complication associated with significant patient morbidity. Octreotide acetate is a somatostatin analogue established in the treatment of chylothorax; however, its utility in the management of cervical chylous fistulae has not been fully evaluated. The investigators hypothesized that chylous fistula can be managed by a combination of octreotide and peripheral total parenteral nutrition (TPN). A retrospective review of cases compiled at our institution from 2009 to 2015 was conducted. Ten patients, all men, were identified as having a postoperative chylous fistula after a neck dissection. All patients were treated with peripheral TPN and intravenous octreotide. Mean age of the patients was 63.0 years (range 49 to 82). Five (50.0%) had a neck dissection for the management of metastatic nasopharyngeal carcinoma and had previous neck irradiation. In 8 (80%) patients, chylous fistula occurred in the left neck. Seven (70.0%) of the leaks occurred within the first 2 postoperative days. Eight (80%) leaks were controlled using TPN and octreotide, with 2 (20%) patients requiring surgical intervention. No factors were significant in the successful conservative management of chylous fistulae. One patient with a chylous fistula of 1,800 ml\/day was managed successfully without surgical intervention. The results of this case series suggest that chylous fistulae may be managed conservatively with octreotide and TPN. However, long-term evaluation is needed to define if and when surgical intervention is required for control.<\/jats:p>","DOI":"10.1177\/014556131709600720","type":"journal-article","created":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T23:45:33Z","timestamp":1543967133000},"page":"264-267","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Conservative Management of Postoperative Chylous Fistula with Octreotide and Peripheral Total Parenteral Nutrition"],"prefix":"10.1177","volume":"96","author":[{"given":"Jason Y.K.","family":"Chan","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eddy W.Y.","family":"Wong","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.K.","family":"Ng","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C. Andrew","family":"van Hasselt","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander C.","family":"Vlantis","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head and Neck Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2017,7,1]]},"reference":[{"key":"bibr1-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0347(199607\/08)18:4<347::AID-HED6>3.0.CO;2-Y"},{"key":"bibr2-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(00)70140-9"},{"key":"bibr3-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1177\/019459988108900413"},{"key":"bibr4-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1002\/lary.23216"},{"key":"bibr5-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1002\/hed.10103"},{"key":"bibr6-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199806000-00027"},{"key":"bibr7-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2354.2009.01086.x"},{"key":"bibr8-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197606000-00008"},{"key":"bibr9-014556131709600720","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2011.02.001"},{"issue":"3","key":"bibr10-014556131709600720","first-page":"86","volume":"48","author":"Benedix F.","year":"2010","journal-title":"S Afr J Surg"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014556131709600720","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/014556131709600720","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:36:09Z","timestamp":1777401369000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/014556131709600720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1177\/014556131709600720"],"URL":"https:\/\/doi.org\/10.1177\/014556131709600720","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]}}}