{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T06:30:32Z","timestamp":1784356232530,"version":"3.55.0"},"reference-count":19,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2018,8,1]],"date-time":"2018-08-01T00:00:00Z","timestamp":1533081600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:p>The relationship between otitis media with effusion (OME) and chronic rhinosinusitis with nasal polyposis (CRSwNP) remains unclear. We conducted a cross-sectional study of 80 consecutively presenting patients\u201442 males and 38 females, aged 15 to 76 years (median: 48)\u2014who were diagnosed with CRSwNP. Our aim was to ascertain the prevalence of OME in CRSwNP patients, to determine whether the severity of CRSwNP affected OME, and to identify risk factors for OME in CRSwNP patients. The severity of CRSwNP was assessed on the basis of nasal symptoms, endoscopic nasal examinations, and Lund-Mackay staging scores. In addition to demographic data, we obtained information on each patient's history of otitis, otoscopic findings, and the results of pure-tone audiometry and tympanometry. We then compared the data between CRSwNP patients with OME (n = 20) and those without (n = 60). In the OME group, a conductive hearing loss was present in 16 patients (80.0%); all patients in the control group had normal hearing. With regard to symptoms, only rhinorrhea appeared to be more common in patients with OME than in those without, although the difference was not statistically significant. We found no significant difference in nasal polyposis grades between the two groups. Also, we found no correlations between the risk of OME and previous surgical treatment, asthma, allergy, aspirin intolerance, aspirin and\/or NSAID intolerance, aspirin and\/or sulfite intolerance, and aspirin-exacerbated respiratory disease. Based on our findings, we conclude that OME occurs frequently during the evolution of CRSwNP, even when the nasal disease is well controlled. This finding suggests the possible presence, in OME and\/or CRSwNP, of a global inflammatory process that involves the epithelium in both the middle ear and upper airway.<\/jats:p>","DOI":"10.1177\/014556131809700803","type":"journal-article","created":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T23:50:02Z","timestamp":1543967402000},"page":"E13-E18","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Chronic Otitis Media with Effusion in Chronic Sinusitis with Polyps"],"prefix":"10.1177","volume":"97","author":[{"given":"Mary","family":"Daval","sequence":"first","affiliation":[{"name":"From the Department of Otorhinolaryngology\u2013Head and Neck Surgery, Fondation Ophtalmologique Adolphe de Rothschild, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herv\u00e9","family":"Picard","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, Fondation Ophtalmologique Adolphe de Rothschild, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emilie","family":"Bequignon","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, H\u00f4pital Intercommunal de Cr\u00e9teil, Cr\u00e9teil, France, and Centre Hospitalier Universitaire Henri-Mondor, Cr\u00e9teil"},{"name":"Inserm Unit 955, Institut Mondor de Recherche Biom\u00e9dicale, Cr\u00e9teil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Bedbeder","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, H\u00f4pital Intercommunal de Cr\u00e9teil, Cr\u00e9teil, France, and Centre Hospitalier Universitaire Henri-Mondor, Cr\u00e9teil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9","family":"Coste","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, H\u00f4pital Intercommunal de Cr\u00e9teil, Cr\u00e9teil, France, and Centre Hospitalier Universitaire Henri-Mondor, Cr\u00e9teil"},{"name":"Inserm Unit 955, Institut Mondor de Recherche Biom\u00e9dicale, Cr\u00e9teil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Denis","family":"Ayache","sequence":"additional","affiliation":[{"name":"From the Department of Otorhinolaryngology\u2013Head and Neck Surgery, Fondation Ophtalmologique Adolphe de Rothschild, Paris"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginie","family":"Escabasse","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, H\u00f4pital Intercommunal de Cr\u00e9teil, Cr\u00e9teil, France, and Centre Hospitalier Universitaire Henri-Mondor, Cr\u00e9teil"},{"name":"Inserm Unit 955, Institut Mondor de Recherche Biom\u00e9dicale, Cr\u00e9teil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,8,1]]},"reference":[{"issue":"4","key":"bibr1-014556131809700803","first-page":"396","volume":"47","author":"Parietti-Winkler C.","year":"2009","journal-title":"Rhinology"},{"key":"bibr2-014556131809700803","doi-asserted-by":"publisher","DOI":"10.4193\/Rhino12.000"},{"key":"bibr3-014556131809700803","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2273.1995.tb00007.x"},{"issue":"4","key":"bibr4-014556131809700803","first-page":"183","volume":"31","author":"Lund V.J.","year":"1993","journal-title":"Rhinology"},{"key":"bibr5-014556131809700803","doi-asserted-by":"publisher","DOI":"10.1016\/S0194-5998(95)70103-6"},{"key":"bibr6-014556131809700803","first-page":"218","volume":"263","author":"Lid\u00e9n G.","year":"1969","journal-title":"Acta Otolaryngol Suppl"},{"key":"bibr7-014556131809700803","unstructured":"R Core Team. 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