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Primary leiomyosarcoma of the parapharyngeal space, however, is extremely rare, as only 4 cases have been previously reported to date. We describe the somewhat urgent case of a primary leiomyosarcoma of the right parapharyngeal space in a 30-year-old man. We also review the diagnostic and therapeutic challenges that clinicians face in managing this rare tumor.<\/jats:p>","DOI":"10.1177\/0145561318097010-1102","type":"journal-article","created":{"date-parts":[[2018,12,4]],"date-time":"2018-12-04T23:48:54Z","timestamp":1543967334000},"page":"E28-E31","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Primary parapharyngeal Leiomyosarcoma: A Case Report"],"prefix":"10.1177","volume":"97","author":[{"given":"Luca Giovanni","family":"Locatello","sequence":"first","affiliation":[{"name":"Division of Otorhinolaryngology Department of Surgery and Translational Medicine, University of Florence Faculty of Medicine and Surgery, Florence, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jano Maria","family":"De Cesare","sequence":"additional","affiliation":[{"name":"Division of Otorhinolaryngology Department of Surgery and Translational Medicine, University of Florence Faculty of Medicine and Surgery, Florence, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cecilia","family":"Taverna","sequence":"additional","affiliation":[{"name":"Division of Pathology Department of Surgery and Translational Medicine, University of Florence Faculty of Medicine and Surgery, Florence, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oreste","family":"Gallo","sequence":"additional","affiliation":[{"name":"Division of Otorhinolaryngology Department of Surgery and Translational Medicine, University of Florence Faculty of Medicine and Surgery, Florence, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2018,10,1]]},"reference":[{"key":"bibr1-0145561318097010-1102","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2013.07.002"},{"key":"bibr2-0145561318097010-1102","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjps.2016.09.026"},{"key":"bibr3-0145561318097010-1102","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2005.01.012"},{"issue":"7","key":"bibr4-0145561318097010-1102","first-page":"E20","volume":"91","author":"Parida P.K.","year":"2012","journal-title":"Ear Nose Throat J"},{"key":"bibr5-0145561318097010-1102","doi-asserted-by":"publisher","DOI":"10.1177\/014556131409300701"},{"key":"bibr6-0145561318097010-1102","doi-asserted-by":"publisher","DOI":"10.1002\/hed.2880140111"},{"key":"bibr7-0145561318097010-1102","unstructured":"National Comprehensive Cancer Network. 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