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We report a case of GCT-ST of the carotid body, the first report of a tumor of this kind arising from this site in the neck. Giant cell tumor of soft tissue is generally considered a benign tumor with low malignant potential; thus, surgical excision is usually curative. However, due to the location and invasive nature of this patient\u2019s tumor, complete excision was not possible. We discuss the implication of this for long-term management of this patient, as well as similarities and differences in clinical presentation, histology, and biological behavior between this case and previously reported cases of GCT-ST.<\/jats:p>","DOI":"10.1177\/0145561319830306","type":"journal-article","created":{"date-parts":[[2019,2,19]],"date-time":"2019-02-19T23:29:59Z","timestamp":1550618999000},"page":"165-168","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Giant Cell Tumor of the Carotid Body: A Rare Tumor in a Novel Location"],"prefix":"10.1177","volume":"98","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2065-8753","authenticated-orcid":false,"given":"Payal","family":"Chowdhary","sequence":"first","affiliation":[{"name":"Cooper Medical School of Rowan University, Camden, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriel S.","family":"Makar","sequence":"additional","affiliation":[{"name":"Cooper Medical School of Rowan University, Camden, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas","family":"Holdbrook","sequence":"additional","affiliation":[{"name":"Department of Pathology, Cooper University Hospital, Camden, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas C.","family":"Spalla","sequence":"additional","affiliation":[{"name":"Division of Otolaryngology, Department of Surgery, Cooper University Hospital, Camden, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,2,19]]},"reference":[{"key":"bibr1-0145561319830306","volume-title":"Practical Soft Tissue Pathology: A Diagnostic Approach E-Book: A Volume in the Pattern Recognition Series","author":"Jason L","year":"2017"},{"key":"bibr2-0145561319830306","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2014.03.013"},{"key":"bibr3-0145561319830306","volume-title":"Enzinger and Weiss\u2019s soft Tissue Tumors","author":"Goldblum JR","year":"2014","edition":"6"},{"key":"bibr4-0145561319830306","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200002000-00011"},{"key":"bibr5-0145561319830306","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197206)29:6<1518::AID-CNCR2820290616>3.0.CO;2-#"},{"key":"bibr6-0145561319830306","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810215)47:4<736::AID-CNCR2820470419>3.0.CO;2-Q"},{"issue":"6","key":"bibr7-0145561319830306","first-page":"319","volume":"1","author":"Trabelsi A","year":"2009","journal-title":"N Am J Med Sci"},{"issue":"1","key":"bibr8-0145561319830306","first-page":"73","volume":"30","author":"Call\u0131 AO","year":"2014","journal-title":"Turk Patoloji Derg"},{"issue":"12","key":"bibr9-0145561319830306","first-page":"ED19","volume":"9","author":"Bandyopadhyay A","year":"2015","journal-title":"J Clin Diagn Res"},{"issue":"2","key":"bibr10-0145561319830306","first-page":"98","volume":"60","author":"Ry\u015b J","year":"2009","journal-title":"Pol J Pathol"},{"key":"bibr11-0145561319830306","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2009.05.015"},{"key":"bibr12-0145561319830306","doi-asserted-by":"publisher","DOI":"10.1002\/path.1711070106"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0145561319830306","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0145561319830306","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0145561319830306","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:37:00Z","timestamp":1777401420000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0145561319830306"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,2,19]]},"references-count":12,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,3]]}},"alternative-id":["10.1177\/0145561319830306"],"URL":"https:\/\/doi.org\/10.1177\/0145561319830306","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,2,19]]}}}