{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:25:41Z","timestamp":1777562741445,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2019,4,8]],"date-time":"2019-04-08T00:00:00Z","timestamp":1554681600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>Gaze-evoked nystagmus is not rare among those who have acute balance problem and may indicate a cerebellar dysfunction that is associated with a broad spectrum of disorders. The aim of this study is to analyze optokinetic response in those patients. Eleven males and 7 females (age range: 25-60, 42.5 [9.75]) with gaze-evoked nystagmus were analyzed with optokinetic test (Micromed Inc). Nystagmus was elicited by a stimulator light spot moving across the patient\u2019s visual field at a target speed of 30 degree\/second. Ten age-matched healthy participants served as controls. The gain and slow-phase velocity difference in oculomotor response from left and right stimulus was compared in patients and the control participants. One-way analysis of variance test was used for multiple variance analysis of the groups. Statistical significance was set at P &lt; .05. Slow-phase velocity of gaze-evoked nystagmus was ranging between 6 and 19 degree\/second. The mean slow-phase velocity of gaze-evoked nystagmus to the right and left was 8.1 (3.81) and 6.8 (4.67) degree\/second, respectively. Optokinetic gain was out of normal limits in 10 (55.5%) patients. Comparison of mean gain difference between the patients and the normal participants was statistically significant ( P = .025). No statistical difference was found in mean slow-phase velocity difference in optokinetic nystagmus between control participants and patients ( P &gt; .05 [.099]). An acute-onset balance problem may be associated with dysfunction of separate populations of neurons in the brainstem and cerebellum even if there is no radiological neuropathy since gaze-evoked nystagmus is a sign of neural integrator dysfunction. Patients with gaze-evoked nystagmus and optokinetic abnormalities may have disruption of cerebellar pathways and should be followed closely.<\/jats:p>","DOI":"10.1177\/0145561319840902","type":"journal-article","created":{"date-parts":[[2019,4,9]],"date-time":"2019-04-09T01:49:59Z","timestamp":1554774599000},"page":"420-424","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Optokinetic Analysis in Patients With Spontaneous Horizontal Gaze-Evoked Nystagmus Without Radiological Neuropathology"],"prefix":"10.1177","volume":"98","author":[{"given":"Sertac","family":"Yetiser","sequence":"first","affiliation":[{"name":"Department of ORL & HNS, Anadolu Medical Center, Kocaeli, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilay","family":"Ince","sequence":"additional","affiliation":[{"name":"Department of ORL & HNS, Anadolu Medical Center, Kocaeli, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Berkay","family":"Yetiser","sequence":"additional","affiliation":[{"name":"School of Engineering, Koc University, Sar\u0131yer, Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,4,8]]},"reference":[{"key":"bibr1-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1159\/000353285"},{"key":"bibr2-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410420616"},{"key":"bibr3-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1152\/jn.1981.46.4.878"},{"key":"bibr4-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410070108"},{"key":"bibr5-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1111\/j.1475-1313.1984.tb00344.x"},{"key":"bibr6-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e318208f4c3"},{"key":"bibr7-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1016\/0168-0102(93)90116-8"},{"key":"bibr8-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(05)51009-4"},{"key":"bibr9-0145561319840902","doi-asserted-by":"publisher","DOI":"10.3109\/09273972.2012.762532"},{"key":"bibr10-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000573"},{"key":"bibr11-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.15-10-06403.1995"},{"key":"bibr12-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1186\/s40673-016-0060-4"},{"key":"bibr13-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.010972"},{"key":"bibr14-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2012-303177"},{"key":"bibr15-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1097\/WNO.0000000000000507"},{"key":"bibr16-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1113\/JP273204"},{"key":"bibr17-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1007\/s004150050478"},{"key":"bibr18-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1016\/S0967-5868(99)90008-5"},{"key":"bibr19-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1159\/000116427"},{"key":"bibr20-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-008-0782-x"},{"key":"bibr21-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/113.4.921"},{"key":"bibr22-0145561319840902","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-015-7773-9"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0145561319840902","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0145561319840902","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0145561319840902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:37:20Z","timestamp":1777401440000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0145561319840902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,4,8]]},"references-count":22,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1177\/0145561319840902"],"URL":"https:\/\/doi.org\/10.1177\/0145561319840902","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,4,8]]}}}