{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:26:15Z","timestamp":1777562775461,"version":"3.51.4"},"reference-count":20,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,6,2]],"date-time":"2019-06-02T00:00:00Z","timestamp":1559433600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2021,2]]},"abstract":"\n Objectives:<\/jats:title>\n To analyze the incidence of developing contralateral M\u00e9ni\u00e8re\u2019s disease (MD) in patients who undergo labyrinthectomy for vestibular dysfunction in unilateral MD.<\/jats:p>\n <\/jats:sec>\n \n Study Design:<\/jats:title>\n Retrospective chart review.<\/jats:p>\n <\/jats:sec>\n \n Participants and Methods:<\/jats:title>\n \n Adult patients with a diagnosis of MD who underwent surgical labyrinthectomy with minimum follow-up of 12 months were included. Patients who experienced chemical labyrinthectomy, surgical labyrinthectomy for a diagnosis other than MD, contralateral ear surgery, or bilateral MD before the labyrinthectomy were excluded. The key outcome measure is whether symptoms of MD developed in the contralateral ear post-labyrinthectomy. Statistical analysis was performed using \u03c7\n 2<\/jats:sup>\n (Fisher exact) test for discrete variables and the Student t test for continuous variables. A P value < .05 was considered significant.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Of the140 patients who underwent labyrinthectomy for intractable vertigo due to unilateral MD, 84 had at least 1 year follow-up appointments. Twelve percent (10\/84) of these patients developed contralateral MD, which was diagnosed by a neuro-otologist based on symptoms consistent with MD, including low-frequency sensorineural hearing loss. Average age in years is 63.12 (10.83; mean [SD]) at time of surgery. Average follow-up was 35.57 (15.89) months (range: 12-69 months).<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n The incidence of contralateral MD development in patients who underwent labyrinthectomy for unilateral MD is 12%. The current literature states that MD has a 30% bilateral involvement rate. Our incidence is significantly lower when compared to the current literature.<\/jats:p>\n <\/jats:sec>","DOI":"10.1177\/0145561319854744","type":"journal-article","created":{"date-parts":[[2019,6,3]],"date-time":"2019-06-03T01:33:42Z","timestamp":1559525622000},"page":"86-89","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Incidence of Developing Contralateral M\u00e9ni\u00e8re\u2019s Disease in Patients Undergoing Transmastoid Labyrinthectomy for Unilateral M\u00e9ni\u00e8re\u2019s Disease"],"prefix":"10.1177","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7339-6830","authenticated-orcid":false,"given":"Bo","family":"Pang","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head & Neck Surgery, St. John Providence Health System\/Michigan State University, Novi, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anya","family":"Costeloe","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head & Neck Surgery, St. John Providence Health System\/Michigan State University, Novi, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neal M.","family":"Jackson","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head & Neck Surgery, St. John Providence Health System\/Michigan State University, Novi, MI, USA"},{"name":"Department of Otology, Neurotology, and Skull Base Surgery, Michigan Ear Institute, Farmington Hills, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seilesh","family":"Babu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head & Neck Surgery, St. John Providence Health System\/Michigan State University, Novi, MI, USA"},{"name":"Department of Otology, Neurotology, and Skull Base Surgery, Michigan Ear Institute, Farmington Hills, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2019,6,2]]},"reference":[{"key":"bibr1-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.58.7.1151"},{"key":"bibr2-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1177\/003591577106400823"},{"key":"bibr3-0145561319854744","first-page":"10","volume":"406","author":"Paparella MM","year":"1984","journal-title":"Acta Otolaryngol Suppl"},{"key":"bibr4-0145561319854744","doi-asserted-by":"publisher","DOI":"10.3109\/00016489.2014.962184"},{"key":"bibr5-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000519"},{"key":"bibr6-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000001576"},{"key":"bibr7-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1016\/j.otot.2016.10.002"},{"key":"bibr8-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200604000-00011"},{"key":"bibr9-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1177\/000348940911801205"},{"key":"bibr10-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1975.00780390022006"},{"key":"bibr11-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1177\/000348949009900705"},{"issue":"5","key":"bibr12-0145561319854744","first-page":"336","volume":"12","author":"Rosenberg S","year":"1991","journal-title":"Am J Otol"},{"key":"bibr13-0145561319854744","doi-asserted-by":"publisher","DOI":"10.3109\/00016488409130984"},{"key":"bibr14-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215116007982"},{"key":"bibr15-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200011000-00018"},{"key":"bibr16-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e318200a0ad"},{"key":"bibr17-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1097\/01.mao.0000233815.71671.6c"},{"key":"bibr18-0145561319854744","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-6665(20)32318-5"},{"key":"bibr19-0145561319854744","first-page":"2672","volume-title":"Otolaryngology-Head & Neck Surgery","author":"Schessel DA","year":"1998"},{"key":"bibr20-0145561319854744","doi-asserted-by":"publisher","DOI":"10.3109\/00016487609120908"}],"container-title":["Ear, Nose & Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0145561319854744","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0145561319854744","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0145561319854744","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:37:22Z","timestamp":1777401442000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/0145561319854744"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,6,2]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1177\/0145561319854744"],"URL":"https:\/\/doi.org\/10.1177\/0145561319854744","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,6,2]]}}}