{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T21:47:31Z","timestamp":1793656051979,"version":"4.5.1"},"reference-count":26,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2019,9,29]],"date-time":"2019-09-29T00:00:00Z","timestamp":1569715200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Vitamin B12 deficiency-induced hyperhomocysteinemia has been associated with impaired microarterial flow, demyelization, and neuronal damage, resulting in cochlear damage and auditory dysfunction. Therefore, we aimed to evaluate the possible vestibular-evoked myogenic potential (VEMP) abnormalities in patients with vitamin B12 deficiency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Method:<\/jats:title>\n                    <jats:p>In this prospective study, 37 patients diagnosed with vitamin B12 deficiency (&lt;220 pg\/mL) were compared with 31 audiologically healthy participants with normal B12 levels. Burst-evoked cervical VEMP (cVEMP) measurements were performed on all participants. Additionally, cVEMP responses were analyzed for P1-N1 latency, interpeak amplitude, and amplitude asymmetry ratio. The results of audiometric examination and VEMP records as well as absent responses were evaluated and compared between groups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The rate of absent VEMP responses was twice as high in the patient group than in the healthy control group (12 vs 6 cases, respectively). Moreover, the mean values of interpeak amplitude in both right and left ears were statistically shorter in the patient group than the control group ( P values = .024 and .007, respectively). Similarly, the mean amplitude asymmetry ratio was statistically higher in the patient group than the control group ( P = .050). There were no statistically significant differences in latency responses between groups. Furthermore, positive, statistically significant correlation was detected between values of the left P1-N1 interpeak amplitude and vitamin B12 levels ( r = 0.287, P = .037).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Increased rates of absent VEMPs and decreased amplitudes with normal latencies are attributed to peripheral vestibular hypofunction in patients with vitamin B12 deficiency.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0145561319878952","type":"journal-article","created":{"date-parts":[[2019,9,30]],"date-time":"2019-09-30T18:02:32Z","timestamp":1569866552000},"page":"NP231-NP235","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Vestibular Evoked Myogenic Potentials in Patients With Low Vitamin B12 Levels"],"prefix":"10.1177","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2008-163X","authenticated-orcid":false,"given":"Do\u011fukan","family":"\u00d6zdemir","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, University of Health Sciences, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5613-3393","authenticated-orcid":false,"given":"Dursun Mehmet","family":"Mehel","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University of Health Sciences, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6mer","family":"K\u00fc\u00e7\u00fck\u00f6ner","sequence":"additional","affiliation":[{"name":"Department of Audiology, Samsun Training and Research Hospital, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130brahim","family":"A\u011fr\u0131","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Samsun Training and Research Hospital, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu\u011fba","family":"Yemi\u015f","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Samsun Training and Research Hospital, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00f6khan","family":"Akg\u00fcl","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Samsun Training and Research Hospital, Samsun, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6155-5988","authenticated-orcid":false,"given":"Abdulkadir","family":"\u00d6zg\u00fcr","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, University 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