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It is difficult to identify which is the original site. There is no specific clinical manifestation of NECs in the ear and throat, and carcinoid syndrome is a rare situation. Surgery is still the preferred treatment for this disease. For patients with metastasis, radiotherapy and\/or chemotherapy are required.<\/jats:p>","DOI":"10.1177\/0145561320943340","type":"journal-article","created":{"date-parts":[[2020,8,4]],"date-time":"2020-08-04T16:27:02Z","timestamp":1596558422000},"page":"117-122","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["A Rare Case of Primary Neuroendocrine Carcinomas in the Ear and Throat and Review of Literatures"],"prefix":"10.1177","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1405-2042","authenticated-orcid":false,"given":"Tianyu","family":"Ma","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, The First Affiliated Hospital of Harbin Medical University, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chunrui","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, The First Affiliated Hospital of Harbin Medical University, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Qin","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, The First Affiliated Hospital of Harbin Medical University, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tianhong","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, The First Affiliated Hospital of Harbin Medical University, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,8,4]]},"reference":[{"key":"bibr1-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1097\/MLG.0b013e3181671b3d"},{"key":"bibr2-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20797"},{"key":"bibr3-0145561320943340","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2015.3606"},{"key":"bibr4-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1177\/014556131609500701"},{"key":"bibr5-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1080\/00016480510038220"},{"key":"bibr6-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880561"},{"key":"bibr7-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlg.0000175069.13685.37"},{"key":"bibr8-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23666"},{"key":"bibr9-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1601400"},{"key":"bibr10-0145561320943340","first-page":"9834750","volume":"2016","author":"Hasan Z","year":"2016","journal-title":"Case Rep Otolaryngol"},{"key":"bibr11-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1016\/j.neo.2017.09.002"},{"key":"bibr12-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1016\/j.otorri.2012.12.002"},{"issue":"5","key":"bibr13-0145561320943340","first-page":"8062","volume":"15","author":"Sato K","year":"2018","journal-title":"Oncol Lett"},{"issue":"3","key":"bibr14-0145561320943340","first-page":"340","volume":"17","author":"Bittencourt AG","year":"2013","journal-title":"Int Arch Otorhinolaryngol"},{"issue":"10","key":"bibr15-0145561320943340","first-page":"927","volume":"21","author":"Chinese Society of Clinical Oncology Neuroendocrine Oncology Expert Committee","year":"2016","journal-title":"Chinese Clin Oncol"},{"key":"bibr16-0145561320943340","doi-asserted-by":"publisher","DOI":"10.1186\/1756-0500-7-532"},{"issue":"7","key":"bibr17-0145561320943340","first-page":"607","volume":"32","author":"Zhang Y","year":"2019","journal-title":"J Cancer Control Treat"}],"container-title":["Ear, Nose &amp; 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